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Query: HLA-DQB1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HLA-DQB1 0 -0.043

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HLA-DQB1 Ubiquitylation K257 -0.043 _SQK(gl)GLLH_
HLA-DQB1 Ubiquitylation K97 -0.619 _AVTPQGRPDAEYWNSQK(gl)EVLEGTR_

Background Information for HLA-DQB1:


Pubmed-HLA-DQB1 »
Uniprot-HLA-DQB1 »
Biogrid-HLA-DQB1 »
ProteomicsDB-HLA-DQB1 »

Tumorportal-HLA-DQB1 »
COSMIC-HLA-DQB1 »
GenomeRNAi-HLA-DQB1 »
Genecards-HLA-DQB1


Protein-protein Interactions for HLA-DQB1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in HLA-DQB1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ig-like_dom IPR007110 0.6
Category members MHC_I/II-like_Ag-recog IPR011162 0.02
Category members MHC_II_b_N IPR000353 0
Category members Ig_C1-set IPR003597 0
Category members CD80_C2-set IPR013162 0


Protein complexes (CORUM database) featuring HLA-DQB1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HLA-DQB1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0006955 immune response Database 1.22
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_889 KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 0 0.9
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0019221 cytokine-mediated signaling pathway Database 0.44
Category members Pathway Pathway_1132 KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION 0 0.3
Category members Pathway Pathway_1161 KEGG_ASTHMA 0 0.26
Category members GO Category GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II Database 0.13
Category members Pathway Pathway_894 KEGG_GRAFT_VERSUS_HOST_DISEASE 0 0.12
Category members Pathway Pathway_767 KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION 0 0.09
Category members GO Category GO:0032395 MHC class II receptor activity Database 0.08
Category members GO Category GO:0030666 endocytic vesicle membrane Database 0.08
Category members GO Category GO:0050852 T cell receptor signaling pathway Database 0.06
Category members GO Category GO:0032588 trans-Golgi network membrane Database 0.05
Category members GO Category GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response Database 0.04
Category members GO Category GO:0019882 antigen processing and presentation Database 0.03
Category members GO Category GO:0042613 MHC class II protein complex Database 0.01
Category members Pathway Pathway_446 KEGG_AUTOIMMUNE_THYROID_DISEASE 0 0
Category members Pathway Pathway_1014 KEGG_VIRAL_MYOCARDITIS 0 0
Category members Pathway Pathway_1217 KEGG_CELL_ADHESION_MOLECULES_CAMS 0 0
Category members Pathway Pathway_395 KEGG_TYPE_I_DIABETES_MELLITUS 0 0
Category members Pathway Pathway_424 KEGG_LEISHMANIA_INFECTION 0 0
Category members Pathway Pathway_905 KEGG_ALLOGRAFT_REJECTION 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0002455 humoral immune response mediated by circulating immunoglobulin Database 0
Category members GO Category GO:0010008 endosome membrane Database 0
Category members GO Category GO:0012507 ER to Golgi transport vesicle membrane Database 0
Category members GO Category GO:0030658 transport vesicle membrane Database 0
Category members GO Category GO:0030669 clathrin-coated endocytic vesicle membrane Database 0
Category members GO Category GO:0031295 T cell costimulation Database 0
Category members GO Category GO:0060333 interferon-gamma-mediated signaling pathway Database 0


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