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Query: HIST2H3C

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HIST2H3C 0 3.278 -0.950 1.680
HIST2H3C 0 3.278 -0.950 1.680 -0.118 0.659
HIST2H3C 0 3.278 -0.950 1.680 -0.645

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HIST2H3C Ubiquitylation K19 -0.191 1.088 _K(gl)QLATK(gl)AAR_
HIST2H3C Ubiquitylation K80 -0.762 0.886 _EIAQDFK(gl)TDLR_
HIST2H3C Ubiquitylation K57 0.195 0.849 _YQK(gl)STELLIR_
HIST2H3C Ubiquitylation K24 0.496 0.281 _K(gl)QLATK(gl)AAR_
HIST2H3C Ubiquitylation K123 -1.638 0.066 _VTIMPK(gl)DIQLAR_
HIST2H3C Ubiquitylation K37 -1.564 _SAPSTGGVK(gl)KPHR_
HIST2H3C Ubiquitylation K38 -1.512 _SAPSTGGVK(gl)KPHR_
HIST2H3C Ubiquitylation K37 -1.968 _SAPATGGVK(gl)KPHR_
HIST2H3C Ubiquitylation K38 -0.934 _SAPATGGVKK(gl)PHR_

Background Information for HIST2H3C:


Pubmed-HIST2H3C »
Uniprot-HIST2H3C »
Biogrid-HIST2H3C »
ProteomicsDB-HIST2H3C »

Tumorportal-HIST2H3C »
COSMIC-HIST2H3C »
GenomeRNAi-HIST2H3C »
Genecards-HIST2H3C


Protein-protein Interactions for HIST2H3C
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in HIST2H3C
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Histone_core_D IPR007125 0.12
Category members Histone-fold IPR009072 0.01
Category members Histone_H3/CENP-A IPR000164 0


Protein complexes (CORUM database) featuring HIST2H3C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HIST2H3C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_351 REACTOME_RNA_POL_I_TRANSCRIPTION 0 8.31
Category members Pathway Pathway_350 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 0 7.97
Category members Pathway Pathway_875 REACTOME_MEIOSIS 0 6.39
Category members GO Category GO:0006334 nucleosome assembly Database 3.77
Category members Pathway Pathway_874 REACTOME_MEIOTIC_RECOMBINATION 0 3.7
Category members Pathway Pathway_1139 REACTOME_RNA_POL_I_PROMOTER_OPENING 0 3.56
Category members GO Category GO:0000786 nucleosome Database 2.41
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_889 KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 0 0.9
Category members Pathway Pathway_920 REACTOME_AMYLOIDS 0 0.68
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07
Category members Pathway Pathway_365 BIOCARTA_CARM_ER_PATHWAY 0 0


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