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bioLOGIC Data

Query: HIST1H1A

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
HIST1H1A	2	-1.450	-0.420	-0.230
HIST1H1A	2	-1.450	-0.420	-0.230	-2.077	-1.246	-0.337	-1.149	-1.118

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
HIST1H1A	Ubiquitylation	K97	0.052	3.473	_GTLVQTK(gl)GTGASGSFK_
HIST1H1A	Ubiquitylation	K75	1.615	2.152	_KALAAAGYDVEK(gl)NNSR_
HIST1H1A	Ubiquitylation	K67	1.076	1.046	_K(gl)ALAAAGYDVEKNNSR_
HIST1H1A	Ubiquitylation	K93	-0.158	0.945	_SLVSK(gl)GTLVQTK_
HIST1H1A	Ubiquitylation	K106	0.973	0.893	_GTGASGSFK(gl)LNKK_
HIST1H1A	Phosphorylation	S36		-0.319	_RKAS(ph)GPPVSELITK_
HIST1H1A	Phosphorylation	T4	-1.741	-0.745	_(ac)SET(ph)APAAPAAPAPAEK_
HIST1H1A	Phosphorylation	S2	-1.308	-1.220	_S(ph)ETAPAAPAAPAPAEK_
HIST1H1A	Phosphorylation	T18	-2.773	-1.986	_(ac)S(ph)ETAPAAPAAPAPAEKT(ph)PVKK_

Background Information for HIST1H1A:

Pubmed-HIST1H1A »

Uniprot-HIST1H1A »

Biogrid-HIST1H1A »

ProteomicsDB-HIST1H1A »

Tumorportal-HIST1H1A »

COSMIC-HIST1H1A »

GenomeRNAi-HIST1H1A »

Genecards-HIST1H1A

Protein-protein Interactions for HIST1H1A

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait CNBP	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CPNE4	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait E4F1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait EBNA1BP2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait FGF10	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait HIST1H1A	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MDK	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MRPS34	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait PRR11	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait PSMF1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait RPL28	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZBTB48	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZC3H3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZCRB1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZFAND2B	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZNF274	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZNF331	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZNF71	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in HIST1H1A

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	Histone_H1/H5_H15	IPR005818	0.14
Category members	Histone_H5	IPR005819	0.08

Protein complexes (CORUM database) featuring HIST1H1A

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	Corum	5611	Emerin complex 24	Database	1.05
Category members	Corum	5615	Emerin complex 52	Database	0.99
Category members	Corum	5609	Emerin regulatory complex	Database	0

Categories featuring HIST1H1A

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005634	nucleus	Database	INF
Category members	GO Category	GO:0006334	nucleosome assembly	Database	3.77
Category members	Pathway	Pathway_876	REACTOME_APOPTOTIC_EXECUTION_PHASE	0	2.5
Category members	GO Category	GO:0000786	nucleosome	Database	2.41
Category members	Pathway	Pathway_837	REACTOME_APOPTOSIS	0	2.39
Category members	GO Category	GO:0003677	DNA binding	Database	1.53
Category members	Pathway	Pathway_955	REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION	0	0.51
Category members	GO Category	GO:0000790	nuclear chromatin	Database	0.46
Category members	GO Category	GO:0007283	spermatogenesis	Database	0