bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: H2AFY

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
H2AFY 1 4.536 0.440 0.350 -0.717 0.162 0.382

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
H2AFY Ubiquitylation K295 1.067 1.894 _TVK(gl)NCLALADDKK_
H2AFY Ubiquitylation K304 1.053 0.925 _NCLALADDK(gl)K_
H2AFY Phosphorylation T178 0.817 0.888 _AASADSTTEGT(ph)PADGFTVLSTK_
H2AFY Ubiquitylation K116 -0.551 0.254 _GVTIASGGVLPNIHPELLAK(gl)K_
H2AFY Ubiquitylation K117 -0.333 -0.043 _GVTIASGGVLPNIHPELLAKK(gl)_
H2AFY Ubiquitylation K121 -0.646 -0.167 _GSK(gl)GKLEAIITPPPAKK_
H2AFY Ubiquitylation K307 0.761 -0.193 _LK(gl)SIAFPSIGSGR_
H2AFY Ubiquitylation K123 -0.548 -0.558 _GK(gl)LEAIITPPPAKK_
H2AFY Phosphorylation T129 -1.725 -1.166 _LEAIIT(ph)PPPAK_
H2AFY Ubiquitylation K167 0.462 _QGEVSK(gl)AASADSTTEGTPADGFTVLSTK_
H2AFY Phosphorylation S170 0.502 _AAS(ph)ADSTTEGTPADGFTVLSTK_
H2AFY Ubiquitylation K292 1.109 _CEELLEK(gl)TVK_
H2AFY Ubiquitylation K305 0.941 _NCLALADDKK(gl)_
H2AFY Ubiquitylation K323 0.614 _NGFPK(gl)QTAAQLILK_

Background Information for H2AFY:


Pubmed-H2AFY »
Uniprot-H2AFY »
Biogrid-H2AFY »
ProteomicsDB-H2AFY »

Tumorportal-H2AFY »
COSMIC-H2AFY »
GenomeRNAi-H2AFY »
Genecards-H2AFY


Protein-protein Interactions for H2AFY
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PHF8 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRPF3 Cat. description Hein, Mann, Cell 2015
Category members IP bait APLF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CENPA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GDI2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H2BA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HMGN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSD3B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYH9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAA40 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait XPC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait XRCC6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZCRB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF428 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in H2AFY
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Histone_H2A IPR002119 0.84
Category members Core_histone_macro-H2A IPR021171 0.22
Category members Histone_core_D IPR007125 0.12
Category members Macro_dom IPR002589 0.03
Category members Histone-fold IPR009072 0.01


Protein complexes (CORUM database) featuring H2AFY
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1225 Ubiquitin E3 ligase (H2AFY, SPOP, CUL3) Database 0.08


Categories featuring H2AFY
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0006334 nucleosome assembly Database 3.77
Category members GO Category GO:0000786 nucleosome Database 2.41
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0001739 sex chromatin Database 1.47
Category members GO Category GO:0000793 condensed chromosome Database 1.32
Category members Pathway Pathway_889 KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 0 0.9
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0007549 dosage compensation Database 0.22
Category members GO Category GO:0016568 chromatin modification Database 0.18
Category members Pathway Pathway_418 PID_ATF2_PATHWAY 0 0.08
Category members GO Category GO:0001740 Barr body Database 0.03


.

© Copyright Svejstrup Laboratory 2015