bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: GTF2B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GTF2B 1 0.345 0.010 -0.230 -1.841 -0.911

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GTF2B Phosphorylation S70 0.024 1.199 _VGDS(ph)QNPLLSDGDLSTMIGK_
GTF2B Ubiquitylation K59 0.815 _TFSNDK(gl)ATKDPSR_
GTF2B Ubiquitylation K100 0.563 _GTGAASFDEFGNSK(gl)YQNRR_
GTF2B Ubiquitylation K149 0.704 _QVYEQK(gl)SLK_
GTF2B Ubiquitylation K178 1.874 _TFK(gl)EICAVSR_

Background Information for GTF2B:


Pubmed-GTF2B »
Uniprot-GTF2B »
Biogrid-GTF2B »
ProteomicsDB-GTF2B »

Tumorportal-GTF2B »
COSMIC-GTF2B »
GenomeRNAi-GTF2B »
Genecards-GTF2B


Protein-protein Interactions for GTF2B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GTF2B Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR2F Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR2G Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015


Protein Domains in GTF2B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TFIIB IPR000812 0
Category members Cyclin_N IPR006671 0
Category members Znf_TFIIB IPR013137 0
Category members TFIIB_cyclin IPR013150 0
Category members Cyclin-like IPR013763 0


Protein complexes (CORUM database) featuring GTF2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2825 BRCA1-RNA polymerase II complex Database 1.38
Category members Corum 103 RNA polymerase II holoenzyme complex Database 1.07
Category members Corum 3066 RNA polymerase II complex, chromatin structure modifying Database 0.92
Category members Corum 3064 RNA polymerase II complex, chromatin structure modifying Database 0.64
Category members Corum 2685 RNA polymerase II (RNAPII) Database 0.12
Category members Corum 493 DAB complex Database 0.04
Category members Corum 1749 SMN-PolII-RHA complex Database 0


Categories featuring GTF2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_376 REACTOME_HIV_LIFE_CYCLE 0 9.45
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_374 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 0 7.57
Category members GO Category GO:0006352 DNA-dependent transcription, initiation Database 3.76
Category members Pathway Pathway_375 REACTOME_RNA_POL_II_TRANSCRIPTION 0 2.46
Category members GO Category GO:0006368 transcription elongation from RNA polymerase II promoter Database 2.03
Category members Pathway Pathway_363 REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS 0 1.84
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0017025 TBP-class protein binding Database 0.35
Category members Pathway Pathway_370 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING 0 0.34
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members GO Category GO:0001047 core promoter binding Database 0.11
Category members Pathway Pathway_381 BIOCARTA_RARRXR_PATHWAY 0 0.08
Category members GO Category GO:0046966 thyroid hormone receptor binding Database 0
Category members Pathway Pathway_856 KEGG_BASAL_TRANSCRIPTION_FACTORS 0 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


.

© Copyright Svejstrup Laboratory 2015