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Query: FYCO1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FYCO1 0 0.597 0.970 -1.080 -1.408 0.596

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FYCO1 Ubiquitylation K416 0.606 0.803 _TK(gl)VEEVNR_

Background Information for FYCO1:


Pubmed-FYCO1 »
Uniprot-FYCO1 »
Biogrid-FYCO1 »
ProteomicsDB-FYCO1 »

Tumorportal-FYCO1 »
COSMIC-FYCO1 »
GenomeRNAi-FYCO1 »
Genecards-FYCO1


Protein-protein Interactions for FYCO1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FYCO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAX6 Cat. description Hein, Mann, Cell 2015
Category members IP bait C17orf59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC101 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC68 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIF1AN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCP10L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRUB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FYCO1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FYVE_PHD IPR011011 1.23
Category members GOLD IPR009038 0.12
Category members tRNA-bd_arm IPR010978 0.08
Category members Znf_FYVE IPR000306 0
Category members Run IPR004012 0
Category members Prefoldin IPR009053 0
Category members Znf_FYVE-rel IPR017455 0


Protein complexes (CORUM database) featuring FYCO1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FYCO1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005770 late endosome Database 0.09
Category members Disease phenotype Nuclear_cataract Nuclear cataract Database 0
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0005776 autophagic vacuole Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0031410 cytoplasmic vesicle Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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