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Query: DERL2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DERL2 0 0.298 1.140 0.560

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DERL2 Ubiquitylation K200 0.298 _ILK(gl)TPSILK_

Background Information for DERL2:


Pubmed-DERL2 »
Uniprot-DERL2 »
Biogrid-DERL2 »
ProteomicsDB-DERL2 »

Tumorportal-DERL2 »
COSMIC-DERL2 »
GenomeRNAi-DERL2 »
Genecards-DERL2


Protein-protein Interactions for DERL2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FZD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HSPA14 Cat. description Hein, Mann, Cell 2015
Category members IP bait KCNK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KCTD5 Cat. description Hein, Mann, Cell 2015
Category members IP bait MASTL Cat. description Hein, Mann, Cell 2015
Category members IP bait REEP5 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM63B Cat. description Hein, Mann, Cell 2015
Category members IP bait FAF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RTN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DERL2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DER1 IPR007599 0.2


Protein complexes (CORUM database) featuring DERL2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 4999 p97/VCP-VIMP-DERL1-DERL2-HRD1-SEL1L complex Database 0.52
Category members Corum 4998 p97/VCP-VIMP-DERL2 complex Database 0.01


Categories featuring DERL2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0030968 endoplasmic reticulum unfolded protein response Database 1.35
Category members GO Category GO:0005769 early endosome Database 1.26
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0030433 ER-associated ubiquitin-dependent protein catabolic process Database 0.33
Category members GO Category GO:0005770 late endosome Database 0.09
Category members GO Category GO:0030970 retrograde protein transport, ER to cytosol Database 0.06
Category members GO Category GO:0001967 suckling behavior Database 0.05
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0030176 integral to endoplasmic reticulum membrane Database 0
Category members GO Category GO:0030307 positive regulation of cell growth Database 0


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