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Query: DDX20

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DDX20 2 2.062 -1.700 3.260 -0.911 -0.594 -0.404
DDX20 2 2.062 -1.700 3.260 -1.460

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DDX20 Phosphorylation S268 1.509 _LNS(ph)SDPSLIGLK_
DDX20 Phosphorylation T531 0.063 0.240 _AT(ph)SPKELGCDR_
DDX20 Phosphorylation S714 -0.225 0.002 _YQES(ph)PGIQM(ox)K_
DDX20 Ubiquitylation K356 0.817 -0.217 _LDAMAKLK(gl)_
DDX20 Phosphorylation S532 -1.143 -0.447 _ATS(ph)PKELGCDR_
DDX20 Ubiquitylation K720 -1.179 _YQESPGIQMK(gl)TR_

Background Information for DDX20:


Pubmed-DDX20 »
Uniprot-DDX20 »
Biogrid-DDX20 »
ProteomicsDB-DDX20 »

Tumorportal-DDX20 »
COSMIC-DDX20 »
GenomeRNAi-DDX20 »
Genecards-DDX20


Protein-protein Interactions for DDX20
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GEMIN5 Cat. description Hein, Mann, Cell 2015
Category members IP bait GEMIN7 Cat. description Hein, Mann, Cell 2015
Category members IP bait KCNK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SNRNP70 Cat. description Hein, Mann, Cell 2015
Category members IP bait STRAP Cat. description Hein, Mann, Cell 2015
Category members IP bait C19orf75 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DDX20
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members DEAD/DEAH_box_helicase_dom IPR011545 0.35
Category members RNA_helicase_DEAD_Q_motif IPR014014 0.24


Protein complexes (CORUM database) featuring DDX20
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1751 SMN complex Database 0.37
Category members Corum 3284 SMN complex (GEMIN5,2,3,4, SMN) Database 0.23
Category members Corum 1143 SMN complex Database 0.14
Category members Corum 1752 SMN complex Database 0.11
Category members Corum 1142 SMN complex Database 0
Category members Corum 1745 SMN complex Database 0
Category members Corum 1749 SMN-PolII-RHA complex Database 0
Category members Corum 1750 PPP4C-PPP4R2-Gemin3-Gemin4 complex Database 0
Category members Corum 3296 SMN complex (GEMIN5,4,3), SMN-independent intermediate Database 0
Category members Corum 824 Anti-SMN protein complex Database 0
Category members Corum 832 Anti-Sm protein complex Database 0


Categories featuring DDX20
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_887 REACTOME_METABOLISM_OF_NON_CODING_RNA 0 4.38
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0004004 ATP-dependent RNA helicase activity Database 1.43
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0017053 transcriptional repressor complex Database 0.28
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0006396 RNA processing Database 0.17
Category members GO Category GO:0000244 spliceosomal tri-snRNP complex assembly Database 0.15
Category members GO Category GO:0048477 oogenesis Database 0.11
Category members GO Category GO:0000387 spliceosomal snRNP assembly Database 0.04
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members Pathway Pathway_1097 BIOCARTA_ETS_PATHWAY 0 0
Category members GO Category GO:0034660 ncRNA metabolic process Database 0
Category members GO Category GO:0050810 regulation of steroid biosynthetic process Database 0


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