bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: DCTN1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DCTN1 0 -1.075 1.450 -0.750 -0.378 -2.511 0.436 0.352
DCTN1 0 -1.075 1.450 -0.750 0.127

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DCTN1 Ubiquitylation K618 0.526 0.373 _LICK(gl)AELIR_

Background Information for DCTN1:


Pubmed-DCTN1 »
Uniprot-DCTN1 »
Biogrid-DCTN1 »
ProteomicsDB-DCTN1 »

Tumorportal-DCTN1 »
COSMIC-DCTN1 »
GenomeRNAi-DCTN1 »
Genecards-DCTN1


Protein-protein Interactions for DCTN1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTR1B Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait C16orf45 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf106 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCTN6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDGFD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RIC8A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS19BP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DCTN1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Tropomyosin IPR000533 0.08
Category members CAP-Gly_domain IPR000938 0.04
Category members Polyketide_synth_docking IPR015083 0


Protein complexes (CORUM database) featuring DCTN1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DCTN1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0031252 cell leading edge Database 2.52
Category members GO Category GO:0000776 kinetochore Database 2.24
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0030968 endoplasmic reticulum unfolded protein response Database 1.35
Category members GO Category GO:0006987 activation of signaling protein activity involved in unfolded protein response Database 1.26
Category members GO Category GO:0005874 microtubule Database 1.21
Category members Pathway Pathway_147 REACTOME_UNFOLDED_PROTEIN_RESPONSE 0 1.08
Category members GO Category GO:0005813 centrosome Database 0.75
Category members Pathway Pathway_1265 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 0 0.6
Category members Pathway Pathway_32 KEGG_HUNTINGTONS_DISEASE 0 0.46
Category members Pathway Pathway_727 REACTOME_MITOTIC_G2_G2_M_PHASES 0 0.46
Category members Pathway Pathway_728 REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES 0 0.4
Category members Pathway Pathway_146 REACTOME_DIABETES_PATHWAYS 0 0.39
Category members GO Category GO:0000922 spindle pole Database 0.35
Category members Pathway Pathway_730 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES 0 0.33
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members Pathway Pathway_562 PID_NCADHERIN_PATHWAY 0 0.29
Category members GO Category GO:0030286 dynein complex Database 0.27
Category members Disease phenotype Amyotrophic_lateral_sclerosis Amyotrophic lateral sclerosis Database 0.21
Category members GO Category GO:0003774 motor activity Database 0.2
Category members Disease phenotype Distal_hereditary_motor_neuropathy_type_7 Distal hereditary motor neuropathy type 7 Database 0.18
Category members GO Category GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II Database 0.13
Category members Pathway Pathway_148 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S 0 0.11
Category members GO Category GO:0008219 cell death Database 0.08
Category members GO Category GO:0048037 cofactor binding Database 0.08
Category members GO Category GO:0016740 transferase activity Database 0.07
Category members GO Category GO:0045502 dynein binding Database 0.04
Category members Pathway Pathway_266 KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION 0 0
Category members Disease phenotype AMYOTROPHIC_LATERAL_SCLEROSIS_1 AMYOTROPHIC LATERAL SCLEROSIS 1 Database 0
Category members GO Category GO:0005869 dynactin complex Database 0
Category members GO Category GO:0007399 nervous system development Database 0


.

© Copyright Svejstrup Laboratory 2015