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Query: CNOT2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CNOT2 0 0.960 -1.010 0.910
CNOT2 0 0.960 -0.480 -0.280

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CNOT2 Phosphorylation S80 -0.345 0.395 _TNSMSSSGLGS(ph)PNR_

Background Information for CNOT2:


Pubmed-CNOT2 »
Uniprot-CNOT2 »
Biogrid-CNOT2 »
ProteomicsDB-CNOT2 »

Tumorportal-CNOT2 »
COSMIC-CNOT2 »
GenomeRNAi-CNOT2 »
Genecards-CNOT2


Protein-protein Interactions for CNOT2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CNOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CNOT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TNKS1BP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BTRC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C2orf29 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAPZA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CNOT7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GADD45B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPBP1L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLKB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MMP7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NANOS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RIBC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEX13A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TOB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WRAP73 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CNOT2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members NOT IPR007282 0


Protein complexes (CORUM database) featuring CNOT2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CNOT2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_310 KEGG_RNA_DEGRADATION 0 0.26
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Database 0.17
Category members Pathway Pathway_842 REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY 0 0.1
Category members GO Category GO:0001104 RNA polymerase II transcription cofactor activity Database 0.08
Category members GO Category GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening Database 0.06
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members Pathway Pathway_841 REACTOME_DEADENYLATION_OF_MRNA 0 0
Category members GO Category GO:0001829 trophectodermal cell differentiation Database 0
Category members GO Category GO:0004535 poly(A)-specific ribonuclease activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006417 regulation of translation Database 0
Category members GO Category GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly Database 0
Category members GO Category GO:0030014 CCR4-NOT complex Database 0
Category members GO Category GO:0031047 gene silencing by RNA Database 0
Category members GO Category GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway Database 0


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