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Query: CLASP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CLASP2 1 3.090 -1.110 -0.564
CLASP2 1 3.090 0.249 0.298

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CLASP2 Ubiquitylation K1425 1.196 0.967 _MQTK(gl)VIER_
CLASP2 Phosphorylation S762 0.315 0.366 _IPRPSVSQGCS(ph)R_
CLASP2 Phosphorylation S241 0.318 0.351 _DKS(ph)FDDEESVDGNRPSSAASAFK_
CLASP2 Phosphorylation S758 -0.210 0.330 _IPRPSVS(ph)QGCSR_
CLASP2 Phosphorylation S560 0.651 0.296 _SSSSS(ph)QESLNRPFSSK_
CLASP2 Phosphorylation S808 0.347 0.264 _VLNTGS(ph)DVEEAVADALK_
CLASP2 Phosphorylation S1264 0.155 _EAMFDDDADQFPDDLS(ph)LDHSDLVAELLK_
CLASP2 Phosphorylation S1268 0.155 _EAMFDDDADQFPDDLS(ph)LDHSDLVAELLK_
CLASP2 Phosphorylation S593 -0.339 0.138 _ASS(ph)LPGSLQR_
CLASP2 Phosphorylation S603 0.514 0.132 _SRS(ph)DIDVNAAAGAK_
CLASP2 Phosphorylation S601 1.688 _S(ph)RSDIDVNAAAGAK_
CLASP2 Phosphorylation T806 0.762 _VLNT(ph)GSDVEEAVADALK_

Background Information for CLASP2:


Pubmed-CLASP2 »
Uniprot-CLASP2 »
Biogrid-CLASP2 »
ProteomicsDB-CLASP2 »

Tumorportal-CLASP2 »
COSMIC-CLASP2 »
GenomeRNAi-CLASP2 »
Genecards-CLASP2


Protein-protein Interactions for CLASP2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPJ;DKFZp667E025 Cat. description Hein, Mann, Cell 2015
Category members IP bait CLASP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CROCC Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MARK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SOGA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CSGALNACT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GORASP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ID2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHDC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAPRE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CLASP2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members HEAT IPR000357 3.83
Category members HEAT_type_2 IPR021133 0.74
Category members CLASP_N_dom IPR024395 0


Protein complexes (CORUM database) featuring CLASP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CLASP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0005938 cell cortex Database 2.26
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0007163 establishment or maintenance of cell polarity Database 1.08
Category members GO Category GO:0034453 microtubule anchoring Database 0.97
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0032587 ruffle membrane Database 0.65
Category members GO Category GO:0051010 microtubule plus-end binding Database 0.47
Category members GO Category GO:0005815 microtubule organizing center Database 0.39
Category members GO Category GO:0031023 microtubule organizing center organization Database 0.38
Category members GO Category GO:0031110 regulation of microtubule polymerization or depolymerization Database 0.35
Category members GO Category GO:0000777 condensed chromosome kinetochore Database 0.32
Category members GO Category GO:0032886 regulation of microtubule-based process Database 0.29
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0005802 trans-Golgi network Database 0.13
Category members GO Category GO:0005881 cytoplasmic microtubule Database 0.04
Category members GO Category GO:0005828 kinetochore microtubule Database 0
Category members GO Category GO:0007020 microtubule nucleation Database 0
Category members GO Category GO:0007026 negative regulation of microtubule depolymerization Database 0
Category members GO Category GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity Database 0
Category members GO Category GO:0016477 cell migration Database 0
Category members GO Category GO:0043515 kinetochore binding Database 0


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