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Query: CLASP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CLASP1 0 3.675 -0.960 1.790 0.173 0.298

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CLASP1 Phosphorylation S600 0.501 0.771 _SRS(ph)DIDVNAAASAK_
CLASP1 Phosphorylation S1196 0.643 0.634 _S(ph)QEDLNEPIKR_
CLASP1 Phosphorylation S797 0.478 0.348 _VLSTS(ph)TDLEAAVADALK_
CLASP1 Phosphorylation S598 0.439 0.280 _S(ph)RSDIDVNAAASAK_
CLASP1 Phosphorylation S646 0.212 0.217 _RQS(ph)SGSATNVASTPDNR_
CLASP1 Phosphorylation S1091 0.125 -0.316 _NSSNTSVGS(ph)PSNTIGR_
CLASP1 Phosphorylation S636 -0.434 _VSSSSGTTPFSSAAALPPGSYAS(ph)LGR_

Background Information for CLASP1:


Pubmed-CLASP1 »
Uniprot-CLASP1 »
Biogrid-CLASP1 »
ProteomicsDB-CLASP1 »

Tumorportal-CLASP1 »
COSMIC-CLASP1 »
GenomeRNAi-CLASP1 »
Genecards-CLASP1


Protein-protein Interactions for CLASP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPJ;DKFZp667E025 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP55 Cat. description Hein, Mann, Cell 2015
Category members IP bait CLASP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MARK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait PHKG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNF41 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SOGA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARHGEF38 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BSG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYBU Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CLASP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members HEAT IPR000357 3.83
Category members HEAT_type_2 IPR021133 0.74
Category members CLASP_N_dom IPR024395 0


Protein complexes (CORUM database) featuring CLASP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CLASP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0005488 binding Database 9.32
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0005938 cell cortex Database 2.26
Category members GO Category GO:0000776 kinetochore Database 2.24
Category members GO Category GO:0051301 cell division Database 1.15
Category members GO Category GO:0007163 establishment or maintenance of cell polarity Database 1.08
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members GO Category GO:0034453 microtubule anchoring Database 0.97
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0005876 spindle microtubule Database 0.68
Category members GO Category GO:0000226 microtubule cytoskeleton organization Database 0.5
Category members GO Category GO:0001578 microtubule bundle formation Database 0.49
Category members GO Category GO:0051010 microtubule plus-end binding Database 0.47
Category members Pathway Pathway_727 REACTOME_MITOTIC_G2_G2_M_PHASES 0 0.46
Category members Pathway Pathway_728 REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES 0 0.4
Category members GO Category GO:0031023 microtubule organizing center organization Database 0.38
Category members Pathway Pathway_730 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES 0 0.33
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0000777 condensed chromosome kinetochore Database 0.32
Category members GO Category GO:0031111 negative regulation of microtubule polymerization or depolymerization Database 0.28
Category members GO Category GO:0051294 establishment of spindle orientation Database 0.28
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0010458 exit from mitosis Database 0.2
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0005881 cytoplasmic microtubule Database 0.04
Category members Pathway Pathway_1031 REACTOME_SIGNALING_BY_ROBO_RECEPTOR 0 0
Category members GO Category GO:0005828 kinetochore microtubule Database 0
Category members GO Category GO:0007020 microtubule nucleation Database 0
Category members GO Category GO:0007026 negative regulation of microtubule depolymerization Database 0
Category members GO Category GO:0030981 cortical microtubule cytoskeleton Database 0
Category members GO Category GO:0043515 kinetochore binding Database 0


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