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Query: CHL1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CHL1 1 4.193

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CHL1 Phosphorylation T91 4.193 _IIPSNNS(ph)GTFR_

Background Information for CHL1:


Pubmed-CHL1 »
Uniprot-CHL1 »
Biogrid-CHL1 »
ProteomicsDB-CHL1 »

Tumorportal-CHL1 »
COSMIC-CHL1 »
GenomeRNAi-CHL1 »
Genecards-CHL1


Protein-protein Interactions for CHL1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CHL1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ig-like_dom IPR007110 0.6
Category members Ig_sub IPR003599 0.43
Category members Immunoglobulin IPR013151 0.23
Category members Ig_sub2 IPR003598 0.21
Category members Fibronectin_type3 IPR003961 0.19
Category members Ig_I-set IPR013098 0.13


Protein complexes (CORUM database) featuring CHL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CHL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0043524 negative regulation of neuron apoptotic process Database 0.66
Category members GO Category GO:0005578 proteinaceous extracellular matrix Database 0.53
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0031175 neuron projection development Database 0.12
Category members GO Category GO:0050890 cognition Database 0.11
Category members Disease phenotype Distal_monosomy_3p Distal monosomy 3p Database 0.04
Category members GO Category GO:0001764 neuron migration Database 0
Category members GO Category GO:0002020 protease binding Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008344 adult locomotory behavior Database 0
Category members GO Category GO:0035640 exploration behavior Database 0
Category members GO Category GO:0045177 apical part of cell Database 0


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