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Query: CEP250

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CEP250 0 3.425 -0.780 0.750 -0.268

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CEP250 Ubiquitylation K1574 0.155 1.217 _MECQQK(gl)LIK_
CEP250 Phosphorylation S2229 0.282 0.334 _LHS(ph)PGATSTAELGSR_
CEP250 Ubiquitylation K1254 1.110 _LHQDLWK(gl)TQQTR_
CEP250 Phosphorylation S2322 -0.190 _AAQAGS(ph)LEISK_

Background Information for CEP250:


Pubmed-CEP250 »
Uniprot-CEP250 »
Biogrid-CEP250 »
ProteomicsDB-CEP250 »

Tumorportal-CEP250 »
COSMIC-CEP250 »
GenomeRNAi-CEP250 »
Genecards-CEP250


Protein-protein Interactions for CEP250
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CEP250 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait C17orf59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C20orf20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC101 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CEP170 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COG3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM167A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LZTFL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUP54 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RALBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYNC Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CEP250
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Prefoldin IPR009053 0


Protein complexes (CORUM database) featuring CEP250
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CEP250
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0008104 protein localization Database 0.5
Category members Pathway Pathway_727 REACTOME_MITOTIC_G2_G2_M_PHASES 0 0.46
Category members Pathway Pathway_728 REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES 0 0.4
Category members GO Category GO:0005815 microtubule organizing center Database 0.39
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members Pathway Pathway_730 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES 0 0.33
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members GO Category GO:0031616 spindle pole centrosome Database 0.27
Category members GO Category GO:0030997 regulation of centriole-centriole cohesion Database 0.27
Category members GO Category GO:0010457 centriole-centriole cohesion Database 0.11
Category members GO Category GO:0005814 centriole Database 0
Category members GO Category GO:0005929 cilium Database 0
Category members GO Category GO:0005932 microtubule basal body Database 0


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