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Query: CDK16

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CDK16 1 4.545 -1.400 2.950
CDK16 1 4.545 -1.400 2.950 -0.510 0.013

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CDK16 Phosphorylation S385 0.649 _HSSIS(ph)PVRLPLNSSLGAELSR_
CDK16 Phosphorylation T514 0.364 0.570 _DSKPIALKEEIVT(ph)PK_
CDK16 Phosphorylation S110 0.566 _RQLS(ph)MTLR_
CDK16 Ubiquitylation K243 0.512 _EVSLLK(gl)DLK_
CDK16 Phosphorylation T209 0.502 _KIS(ph)TEDINKR_
CDK16 Phosphorylation S251 0.931 0.143 _RVS(ph)LSEIGFGK_
CDK16 Phosphorylation S236 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK16 Phosphorylation S249 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK16 Phosphorylation S208 0.508 0.023 _KIS(ph)TEDINK_
CDK16 Phosphorylation S217 -0.051 0.003 _RLS(ph)LPADIR_
CDK16 Phosphorylation S420 0.004 -0.202 _ES(ph)KGSPVFLPR_
CDK16 Phosphorylation S423 -0.155 -0.297 _GS(ph)PVFLPR_
CDK16 Phosphorylation S193 -0.305 -0.461 _MGS(ph)DGESDQASATSSDEVQS(ph)PVR_
CDK16 Phosphorylation S176 -0.089 -0.530 _M(ox)GS(ph)DGESDQASATSSDEVQS(ph)PVR_
CDK16 Phosphorylation S253 -0.670 _RVSLS(ph)EIGFGK_
CDK16 Phosphorylation S236 -0.603 -0.685 _LTLNS(ph)PIFDKPLSR_
CDK16 Phosphorylation T1244 -0.956 _RT(ph)PTMPQEEAAACPPHILPPEK_
CDK16 Phosphorylation S1082 -1.661 -0.980 _KETTSGTSTEPVKNS(ph)SPAPPQPAPGK_
CDK16 Phosphorylation S1083 -1.093 -1.330 _NSS(ph)PAPPQPAPGK_
CDK16 Phosphorylation T692 -0.765 -1.849 _AIT(ph)PPQQPYK_
CDK16 Phosphorylation S681 -2.532 -2.051 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK16 Phosphorylation S685 -2.729 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_

Background Information for CDK16:


Pubmed-CDK16 »
Uniprot-CDK16 »
Biogrid-CDK16 »
ProteomicsDB-CDK16 »

Tumorportal-CDK16 »
COSMIC-CDK16 »
GenomeRNAi-CDK16 »
Genecards-CDK16


Protein-protein Interactions for CDK16
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK16 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MLLT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUP54 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CDK16
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring CDK16
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CDK16
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0008021 synaptic vesicle Database 0.28
Category members GO Category GO:0006887 exocytosis Database 0.2
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0031175 neuron projection development Database 0.12
Category members GO Category GO:0031234 extrinsic to cytoplasmic side of plasma membrane Database 0.1
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0004693 cyclin-dependent protein serine/threonine kinase activity Database 0.08
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0007283 spermatogenesis Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0030133 transport vesicle Database 0
Category members GO Category GO:0030252 growth hormone secretion Database 0
Category members GO Category GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus Database 0


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