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Query: CAP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CAP1 0 -1.648 -0.450 1.100 0.499 -0.364

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CAP1 Phosphorylation S308 -1.510 -1.436 _SGPKPFSAPKPQTS(ph)PSPK_
CAP1 Phosphorylation T307 -1.904 -1.464 _SGPKPFSAPKPQT(ph)SPSPK_
CAP1 Ubiquitylation K398 0.063 _DVK(gl)VQVMGK_

Background Information for CAP1:


Pubmed-CAP1 »
Uniprot-CAP1 »
Biogrid-CAP1 »
ProteomicsDB-CAP1 »

Tumorportal-CAP1 »
COSMIC-CAP1 »
GenomeRNAi-CAP1 »
Genecards-CAP1


Protein-protein Interactions for CAP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait BCL7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BCL7C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CFL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TWF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CAP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Adenylate_cyclase-assoc_CAP_C IPR013912 0.17
Category members CARP_motif IPR006599 0.13
Category members Adenylate_cyclase-assoc_CAP_N IPR013992 0


Protein complexes (CORUM database) featuring CAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2255 Cofilin-actin-CAP1 complex Database 0


Categories featuring CAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0007163 establishment or maintenance of cell polarity Database 1.08
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members Pathway Pathway_509 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES 0 0.62
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0030168 platelet activation Database 0.13
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members Pathway Pathway_56 REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 0 0.11
Category members GO Category GO:0030864 cortical actin cytoskeleton Database 0.06
Category members Pathway Pathway_236 BIOCARTA_MPR_PATHWAY 0 0.06
Category members GO Category GO:0001667 ameboidal cell migration Database 0.04
Category members Pathway Pathway_1031 REACTOME_SIGNALING_BY_ROBO_RECEPTOR 0 0
Category members Pathway Pathway_55 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ 0 0
Category members GO Category GO:0000902 cell morphogenesis Database 0
Category members GO Category GO:0002576 platelet degranulation Database 0
Category members GO Category GO:0006898 receptor-mediated endocytosis Database 0
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007190 activation of adenylate cyclase activity Database 0


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