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Query: CAND1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CAND1 2 3.563 -0.720 0.390 -1.046 1.059 -0.316 0.107 0.156

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CAND1 Ubiquitylation K574 0.835 1.669 _DLFTCTIK(gl)R_
CAND1 Ubiquitylation K355 1.318 1.197 _AAAK(gl)CLDAVVSTR_
CAND1 Ubiquitylation K577 0.292 0.893 _LK(gl)AADIDQEVKER_
CAND1 Ubiquitylation K60 0.342 0.471 _LLEDK(gl)NGEVQNLAVK_
CAND1 Ubiquitylation K51 0.633 _VVK(gl)MILK_
CAND1 Ubiquitylation K826 1.544 _EGPAVVGQFIQDVK(gl)NSR_

Background Information for CAND1:


Pubmed-CAND1 »
Uniprot-CAND1 »
Biogrid-CAND1 »
ProteomicsDB-CAND1 »

Tumorportal-CAND1 »
COSMIC-CAND1 »
GenomeRNAi-CAND1 »
Genecards-CAND1


Protein-protein Interactions for CAND1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CUL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL4A Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL4B Cat. description Hein, Mann, Cell 2015
Category members IP bait NEDD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL13RA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CAND1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members HEAT IPR000357 3.83
Category members TATA-bd_TIP120 IPR013932 0.18


Protein complexes (CORUM database) featuring CAND1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 219 CAND1-CUL1-RBX1 complex Database 0.06
Category members Corum 221 CAND1-CUL2-RBX1 complex Database 0.06
Category members Corum 222 CAND1-CUL3-RBX1 complex Database 0.06
Category members Corum 223 CAND1-CUL4A-RBX1 complex Database 0.06
Category members Corum 224 CAND1-CUL4B-RBX1 complex Database 0.06


Categories featuring CAND1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0031461 cullin-RING ubiquitin ligase complex Database 0.77
Category members GO Category GO:0017025 TBP-class protein binding Database 0.35
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0000151 ubiquitin ligase complex Database 0.24
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0043086 negative regulation of catalytic activity Database 0
Category members GO Category GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly Database 0


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