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Query: ARID2

This is a cancer-associated gene according to the Broad and Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARID2 0 1.222 0.220 -0.610 0.713 -0.130 0.978 0.294 0.323

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARID2 Phosphorylation S689 -0.677 -1.105 _IPQNPS(ph)PHTHQQQNAPVTVIQSK_
ARID2 Ubiquitylation K7 0.027 _(ac)ANSTGK(gl)APPDER_
ARID2 Ubiquitylation K581 0.093 _TVFPNHTVK(gl)R_
ARID2 Ubiquitylation K1241 0.826 _GDK(gl)IICQK_

Background Information for ARID2:


Pubmed-ARID2 »
Uniprot-ARID2 »
Biogrid-ARID2 »
ProteomicsDB-ARID2 »

Tumorportal-ARID2 »
COSMIC-ARID2 »
GenomeRNAi-ARID2 »
Genecards-ARID2


Protein-protein Interactions for ARID2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AP4M1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BCL7C Cat. description Hein, Mann, Cell 2015
Category members IP bait CD14 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDKN2AIP Cat. description Hein, Mann, Cell 2015
Category members IP bait EGR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KPNA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMARCC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait WDR48 Cat. description Hein, Mann, Cell 2015
Category members IP bait BCL7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BCL7C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DPF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LHX4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUP50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMARCC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMARCD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMARCE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SS18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF23 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARID2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members ARID/BRIGHT_DNA-bd IPR001606 0
Category members DNA-bd_RFX IPR003150 0


Protein complexes (CORUM database) featuring ARID2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 554 PBAF complex (Polybromo- and BAF containing complex) Database 1.57
Category members Corum 565 PBAF complex (Polybromo- and BAF containing complex) Database 1.57
Category members Corum 149 PBAF complex (Polybromo- and BAF containing complex) Database 1.36
Category members Corum 1238 PBAF complex (Polybromo- and BAF containing complex) Database 1.16
Category members Corum 556 PBAF complex (Polybromo- and BAF containing complex) Database 1.16


Categories featuring ARID2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005488 binding Database 9.32
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0006337 nucleosome disassembly Database 3
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Human mutations Broad_cancer_genes Broad cancer genes (Lawrence et al., 2014) literature 1.14
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Human mutations pubmedid:24460190 The molecular pathology of melanoma: an integrated taxonomy of melanocytic neoplasia (Bastian, 2014). Research article 0.88
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0016568 chromatin modification Database 0.18
Category members Human mutations pubmedid:22817889 A Landscape of Driver Mutations in Melanoma (Hodis et al, Cell 2012) Research article 0.15
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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