bioLOGIC Category
Results for the Category
A Landscape of Driver Mutations in Melanoma (Hodis et al, Cell 2012)
(pubmedid:22817889)
| RNAi screen result
|
RNAPII IP (MG132) |
CSB IP |
CSB IP (MG132) |
Chrom. |
Chrom. (MG132) |
Ubi /Phospo |
Ubi /Phospho (MG132) |
| W |
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| Gene name |
MGoogle Score |
RNAi high |
RNAi low |
RNAPII-IP (MG132) |
CSB-IP |
CSB-IP (MG132) |
Chrom. |
Chrom. (MG132) |
|
STK19
|
2
|
-2.520
|
5.040
|
|
|
3.354
|
|
|
|
TACC1
|
1
|
-0.060
|
-0.800
|
|
|
|
|
|
|
PPP6C
|
0
|
0.340
|
-0.620
|
0.715
|
-0.944
|
-0.116
|
|
0.577
|
|
RAC1
|
0
|
-0.580
|
1.580
|
0.486
|
|
|
-0.364
|
-0.568
|
|
ARID2
|
0
|
0.220
|
-0.610
|
0.713
|
-0.130
|
0.978
|
0.294
|
0.323
|
| Gene name |
PTM type |
PTM site |
UV |
UV (MG132) |
Sequence |
|
ARID2
|
Ubiquitylation
|
K7
|
0.027
|
|
_(ac)ANSTGK(gl)APPDER_
|
|
ARID2
|
Ubiquitylation
|
K581
|
0.093
|
|
_TVFPNHTVK(gl)R_
|
|
ARID2
|
Phosphorylation
|
S689
|
-0.677
|
-1.105
|
_IPQNPS(ph)PHTHQQQNAPVTVIQSK_
|
|
ARID2
|
Ubiquitylation
|
K1241
|
0.826
|
|
_GDK(gl)IICQK_
|
|
PPP6C
|
Ubiquitylation
|
K25
|
|
-0.474
|
_YLPENDLK(gl)R_
|
|
RAC1
|
Ubiquitylation
|
K115
|
-1.745
|
-0.215
|
_AK(gl)WYPEVR_
|
|
RAC1
|
Ubiquitylation
|
K142
|
0.492
|
|
_LDLRDDK(gl)DTIEK_
|
|
RAC1
|
Ubiquitylation
|
K152
|
0.099
|
-0.292
|
_K(gl)LTPITYPQGLAMAK_
|
|
RAC1
|
Ubiquitylation
|
K166
|
-0.981
|
-0.655
|
_LTPITYPQGLAMAK(gl)EIGAVK_
|
|
RAC1
|
Ubiquitylation
|
K172
|
1.026
|
0.412
|
_EIGAVK(gl)YLECSALTQR_
|
|
RAC1
|
Ubiquitylation
|
K185
|
-0.113
|
0.578
|
_GLK(gl)TVFDEAIR_
|
|
RAC1
|
Ubiquitylation
|
K202
|
-1.379
|
-1.447
|
_AVLCPPPVK(gl)KR_
|
|
RAC1
|
Ubiquitylation
|
K203
|
-1.708
|
-1.447
|
_AVLCPPPVKK(gl)_
|
|
TACC1
|
Phosphorylation
|
S44
|
-0.293
|
-0.032
|
_GGAAGEDEAGGPEGDPEEEDS(ph)QAETK_
|
|
TACC1
|
Phosphorylation
|
S91
|
0.291
|
1.551
|
_S(ph)QESQEADEQLVAEVVEK_
|
|
TACC1
|
Phosphorylation
|
S94
|
|
1.530
|
_SQES(ph)QEADEQLVAEVVEK_
|
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