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Query: AP3S2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AP3S2 0 -0.365 -0.930 0.720

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AP3S2 Ubiquitylation K350 0.204 _LEK(gl)SEGGLSAAPAR_
AP3S2 Ubiquitylation K367 -1.289 -0.624 _AVSAVK(gl)NINLPEIPR_

Background Information for AP3S2:





Protein-protein Interactions for AP3S2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AP3M1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AP3M2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM63A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AP3S2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Longin-like_dom IPR011012 0.34
Category members AP_complex_ssu IPR016635 0.31
Category members AP_mu_sigma_su IPR022775 0.25


Protein complexes (CORUM database) featuring AP3S2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 59 AP3 adapter complex Database 0.58
Category members Corum 2307 AP3D1-AP3S2 complex Database 0.24
Category members Corum 652 AP3-BLOC1 complex Database 0


Categories featuring AP3S2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0008565 protein transporter activity Database 0.26
Category members GO Category GO:0030123 AP-3 adaptor complex Database 0.05
Category members Pathway Pathway_74 KEGG_LYSOSOME 0 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0008089 anterograde axon cargo transport Database 0
Category members GO Category GO:0030117 membrane coat Database 0
Category members GO Category GO:0048490 anterograde synaptic vesicle transport Database 0


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