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Query: AIMP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AIMP1 0 0.226 -0.220 0.620 -0.699 -0.552 -0.431

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AIMP1 Ubiquitylation K9 -0.014 0.834 _MANNDAVLK(gl)R_
AIMP1 Ubiquitylation K312 0.335 0.619 _AQTMSNSGIK(gl)_
AIMP1 Ubiquitylation K47 0.454 0.365 _AILQATLREEKK(gl)_
AIMP1 Ubiquitylation K35 -1.334 _EK(gl)AILQATLR_

Background Information for AIMP1:


Pubmed-AIMP1 »
Uniprot-AIMP1 »
Biogrid-AIMP1 »
ProteomicsDB-AIMP1 »

Tumorportal-AIMP1 »
COSMIC-AIMP1 »
GenomeRNAi-AIMP1 »
Genecards-AIMP1


Protein-protein Interactions for AIMP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EEF1A1;EEF1A1P5 Cat. description Hein, Mann, Cell 2015
Category members IP bait SDCCAG8 Cat. description Hein, Mann, Cell 2015
Category members IP bait AIMP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KARS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LARS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait QARS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RARS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDCBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AIMP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members NA-bd_OB-fold IPR012340 4.37
Category members t-SNARE IPR010989 0.04
Category members NUDE_C IPR006964 0


Protein complexes (CORUM database) featuring AIMP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3040 Multisynthetase complex Database 1.78


Categories featuring AIMP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members Pathway Pathway_201 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION 0 3.57
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members Pathway Pathway_202 REACTOME_TRNA_AMINOACYLATION 0 1.34
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0005125 cytokine activity Database 1.06
Category members GO Category GO:0007267 cell-cell signaling Database 0.94
Category members GO Category GO:0006418 tRNA aminoacylation for protein translation Database 0.91
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0006954 inflammatory response Database 0.49
Category members GO Category GO:0006006 glucose metabolic process Database 0.28
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0017101 aminoacyl-tRNA synthetase multienzyme complex Database 0.11
Category members GO Category GO:0006935 chemotaxis Database 0.09
Category members GO Category GO:0050900 leukocyte migration Database 0.04
Category members GO Category GO:0000049 tRNA binding Database 0
Category members GO Category GO:0001525 angiogenesis Database 0
Category members GO Category GO:0001937 negative regulation of endothelial cell proliferation Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0009611 response to wounding Database 0
Category members GO Category GO:0030133 transport vesicle Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0


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