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Query: AES

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AES 0 -1.237 -0.830 1.120 -1.378

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AES Ubiquitylation K54 0.449 _LASEK(gl)SEMQR_
AES Ubiquitylation K83 0.433 _QAEIVK(gl)R_
AES Ubiquitylation K112 -1.428 -0.846 _AK(gl)QVTAPELNSIIR_

Background Information for AES:


Pubmed-AES »
Uniprot-AES »
Biogrid-AES »
ProteomicsDB-AES »

Tumorportal-AES »
COSMIC-AES »
GenomeRNAi-AES »
Genecards-AES


Protein-protein Interactions for AES
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ECT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait FGFR1OP Cat. description Hein, Mann, Cell 2015
Category members IP bait LCK Cat. description Hein, Mann, Cell 2015
Category members IP bait HLX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RIPPLY1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RIPPLY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STARD7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TLE4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VENTX Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AES
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Groucho/TLE_N IPR005617 0


Protein complexes (CORUM database) featuring AES
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring AES
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_199 PID_BETA_CATENIN_NUC_PATHWAY 0 0.53
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members GO Category GO:0032091 negative regulation of protein binding Database 0.08
Category members Pathway Pathway_942 PID_PS1_PATHWAY 0 0.03
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0070555 response to interleukin-1 Database 0.02
Category members Pathway Pathway_290 WNT_SIGNALING 0 0
Category members GO Category GO:0001501 skeletal system development Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0009887 organ morphogenesis Database 0
Category members GO Category GO:0010629 negative regulation of gene expression Database 0
Category members GO Category GO:0031668 cellular response to extracellular stimulus Database 0
Category members GO Category GO:0040008 regulation of growth Database 0
Category members GO Category GO:0060761 negative regulation of response to cytokine stimulus Database 0


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