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Query: ACACA

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ACACA 0 3.909 -0.097 0.638 0.222

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ACACA Phosphorylation S80 0.173 1.085 _SSM(ox)S(ph)GLHLVK_
ACACA Phosphorylation S29 0.503 0.908 _FIIGSVSEDNS(ph)EDEISNLVK_
ACACA Ubiquitylation K1076 0.706 0.806 _TTNAK(gl)VALR_
ACACA Phosphorylation S50 0.771 _EGSLS(ph)PASVGSDTLSDLGISSLQDGLALHIR_
ACACA Ubiquitylation K2302 0.617 _DYVLK(gl)QIR_
ACACA Phosphorylation S25 0.549 -0.077 _FIIGSVS(ph)EDNSEDEISNLVK_
ACACA Phosphorylation S5 -0.181 _(ac)MDEPS(ph)PLAQPLELNQHSR_
ACACA Ubiquitylation K1759 -0.633 _YLYLTPQDYK(gl)R_
ACACA Ubiquitylation K1929 -0.815 _IIEFVPTK(gl)TPYDPR_
ACACA Phosphorylation S1259 -1.075 _IFDEVMGCFSDS(ph)PPQS(ph)PTFPEAGHTSLYDEDKVPR_

Background Information for ACACA:


Pubmed-ACACA »
Uniprot-ACACA »
Biogrid-ACACA »
ProteomicsDB-ACACA »

Tumorportal-ACACA »
COSMIC-ACACA »
GenomeRNAi-ACACA »
Genecards-ACACA


Protein-protein Interactions for ACACA
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SHOC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait C20orf195 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C4orf26 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS3BP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OAS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SGCZ Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ACACA
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring ACACA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ACACA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_28 KEGG_PROPANOATE_METABOLISM 0 1.89
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_16 KEGG_PYRUVATE_METABOLISM 0 1.34
Category members Pathway Pathway_5 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM 0 0.9
Category members Pathway Pathway_123 BIOCARTA_CHREBP2_PATHWAY 0 0.61
Category members GO Category GO:0051289 protein homotetramerization Database 0.44
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0006767 water-soluble vitamin metabolic process Database 0.27
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members GO Category GO:0006766 vitamin metabolic process Database 0.23
Category members GO Category GO:0006112 energy reserve metabolic process Database 0.21
Category members Pathway Pathway_44 KEGG_INSULIN_SIGNALING_PATHWAY 0 0.21
Category members Pathway Pathway_6 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS 0 0.2
Category members GO Category GO:0004075 biotin carboxylase activity Database 0.13
Category members GO Category GO:0008716 D-alanine-D-alanine ligase activity Database 0.13
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0035338 long-chain fatty-acyl-CoA biosynthetic process Database 0.1
Category members Pathway Pathway_2 REACTOME_TRIGLYCERIDE_BIOSYNTHESIS 0 0.08
Category members GO Category GO:0031325 positive regulation of cellular metabolic process Database 0.04
Category members GO Category GO:0006768 biotin metabolic process Database 0.02
Category members Pathway Pathway_155 BIOCARTA_LEPTIN_PATHWAY 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0001894 tissue homeostasis Database 0
Category members GO Category GO:0003989 acetyl-CoA carboxylase activity Database 0
Category members GO Category GO:0006084 acetyl-CoA metabolic process Database 0
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0006633 fatty acid biosynthetic process Database 0
Category members GO Category GO:0006853 carnitine shuttle Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0016874 ligase activity Database 0
Category members GO Category GO:0019432 triglyceride biosynthetic process Database 0
Category members GO Category GO:0044255 cellular lipid metabolic process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0055088 lipid homeostasis Database 0


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