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Query: ABCD3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ABCD3 1 3.634 0.430 -0.210
ABCD3 1 3.634 0.430 -0.210 0.177 0.367

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ABCD3 Ubiquitylation K260 1.051 0.695 _MTITEQK(gl)YEGEYR_
ABCD3 Ubiquitylation K6 -0.659 -0.529 _AAFSK(gl)YLTAR_
ABCD3 Ubiquitylation K533 2.395 -0.758 _DQVIYPDGREDQK(gl)R_
ABCD3 Ubiquitylation K39 -1.169 _ALGLHGKK(gl)_

Background Information for ABCD3:


Pubmed-ABCD3 »
Uniprot-ABCD3 »
Biogrid-ABCD3 »
ProteomicsDB-ABCD3 »

Tumorportal-ABCD3 »
COSMIC-ABCD3 »
GenomeRNAi-ABCD3 »
Genecards-ABCD3


Protein-protein Interactions for ABCD3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP2A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait C1QBP Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM134A Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM82A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait KRAS Cat. description Hein, Mann, Cell 2015
Category members IP bait KTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH14 Cat. description Hein, Mann, Cell 2015
Category members IP bait PTPN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB7A Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM63B Cat. description Hein, Mann, Cell 2015
Category members IP bait VAPA Cat. description Hein, Mann, Cell 2015


Protein Domains in ABCD3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members AAA+_ATPase IPR003593 0.38
Category members ABC1_TM_dom IPR011527 0.33
Category members ABC_transporter-like IPR003439 0.15
Category members FA_transporter IPR005283 0
Category members ABC_Peroxi_TM IPR010509 0


Protein complexes (CORUM database) featuring ABCD3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ABCD3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0016887 ATPase activity Database 2.28
Category members GO Category GO:0006200 ATP catabolic process Database 2.13
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0005782 peroxisomal matrix Database 0.23
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members Pathway Pathway_756 KEGG_ABC_TRANSPORTERS 0 0.13
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0042626 ATPase activity, coupled to transmembrane movement of substances Database 0.09
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0042760 very long-chain fatty acid catabolic process Database 0.05
Category members GO Category GO:0005778 peroxisomal membrane Database 0.01
Category members Pathway Pathway_25 KEGG_PEROXISOME 0 0
Category members Pathway Pathway_757 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS 0 0
Category members Pathway Pathway_758 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT 0 0
Category members GO Category GO:0005777 peroxisome Database 0
Category members GO Category GO:0006635 fatty acid beta-oxidation Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0007031 peroxisome organization Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0


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