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Progressive non-fluent aphasia
(Progressive_non-fluent_aphasia)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
VCP 2 1.650 -0.640 -0.182 0.578 -0.596 0.007 -0.036
PSEN1 0 0.930 -1.110
CHMP2B 0 -0.500 1.180
MAPT 0 -0.190 0.150

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CHMP2B Ubiquitylation K195 -0.063 _SLPSASTSK(gl)ATISDEEIER_
CHMP2B Phosphorylation S199 0.711 0.812 _ATIS(ph)DEEIER_
MAPT Phosphorylation S437 -2.106 -1.602 _HPTPGSSDPLIQPSSPAVCPEPPS(ph)SPK_
MAPT Phosphorylation S438 -2.106 -1.602 _HPTPGSSDPLIQPSSPAVCPEPPS(ph)SPK_
MAPT Phosphorylation S516 -0.589 _SGYSS(ph)PGSPGTPGSR_
MAPT Phosphorylation S519 -0.792 -1.278 _SGYSSPGS(ph)PGTPGSR_
MAPT Phosphorylation T548 -0.976 -0.803 _VAVVRT(ph)PPKS(ph)PSSAK_
MAPT Phosphorylation S552 -0.811 -0.801 _VAVVRT(ph)PPKS(ph)PSSAK_
MAPT Phosphorylation S717 -0.091 -0.193 _SPVVS(ph)GDTSPR_
MAPT Phosphorylation T720 -0.287 0.006 _SPVVSGDT(ph)SPR_
MAPT Phosphorylation S721 -0.091 -0.203 _SPVVSGDTS(ph)PR_
MAPT Phosphorylation S729 -0.160 _HLSNVS(ph)STGSIDMVDSPQLATLADEVSASLAK_
MAPT Phosphorylation S733 -0.413 -0.151 _HLSNVSSTGS(ph)IDMVDSPQLATLADEVSASLAK_
PSEN1 Phosphorylation S313 0.844 _VSKNS(ph)KYNAESTER_
PSEN1 Ubiquitylation K314 0.016 0.414 _NSK(gl)YNAESTER_
PSEN1 Phosphorylation S366 -0.340 0.055 _AAVQELSS(ph)SILAGEDPEER_
PSEN1 Phosphorylation S367 0.005 0.066 _AAVQELSSS(ph)ILAGEDPEER_
VCP Phosphorylation S3 0.795 1.142 _(ac)AS(ph)GADSKGDDLSTAILK_
VCP Phosphorylation S7 0.312 0.941 _(ac)ASGADS(ph)KGDDLSTAILK_
VCP Ubiquitylation K8 -0.439 -0.154 _(ac)ASGADSK(gl)GDDLSTAILK_
VCP Ubiquitylation K18 -0.452 0.181 _GDDLSTAILK(gl)QK_
VCP Ubiquitylation K20 -0.512 0.529 _(ac)ASGADSKGDDLSTAILKQK(gl)_
VCP Ubiquitylation K60 0.678 0.493 _GDTVLLK(gl)GKK_
VCP Ubiquitylation K81 0.084 _EAVCIVLSDDTCSDEK(gl)IR_
VCP Ubiquitylation K109 -0.847 -0.260 _LGDVISIQPCPDVK(gl)YGK(gl)R_
VCP Ubiquitylation K112 -0.736 -0.276 _LGDVISIQPCPDVK(gl)YGK(gl)R_
VCP Ubiquitylation K148 -0.262 -0.087 _K(gl)GDIFLVR_
VCP Ubiquitylation K211 1.383 0.902 _K(gl)QLAQIK_
VCP Ubiquitylation K236 -0.526 -0.178 _AIGVK(gl)PPR_
VCP Ubiquitylation K251 -0.110 _GILLYGPPGTGK(gl)TLIAR_
VCP Ubiquitylation K336 0.522 _IVSQLLTLMDGLK(gl)QR_
VCP Ubiquitylation K386 1.339 0.706 _LEILQIHTK(gl)NM(ox)K_
VCP Ubiquitylation K389 0.568 1.195 _LEILQIHTKNMK(gl)_
VCP Ubiquitylation K505 0.377 0.794 _FLK(gl)FGMTPSK_
VCP Ubiquitylation K524 -0.528 _GVLFYGPPGCGK(gl)TLLAK_
VCP Ubiquitylation K529 -0.250 _GVLFYGPPGCGKTLLAK(gl)_
VCP Ubiquitylation K565 0.645 0.689 _EIFDK(gl)AR_
VCP Ubiquitylation K615 1.209 1.270 _VINQILTEMDGMSTKK(gl)_
VCP Ubiquitylation K651 -1.709 -0.719 _LDQLIYIPLPDEK(gl)SR_
VCP Ubiquitylation K658 0.362 0.711 _VAILK(gl)ANLR_
VCP Ubiquitylation K663 -0.839 _K(gl)SPVAKDVDLEFLAK_
VCP Ubiquitylation K668 -0.536 0.265 _SPVAK(gl)DVDLEFLAK_
VCP Ubiquitylation K696 1.574 1.691 _ACK(gl)LAIR_
VCP Ubiquitylation K754 0.510 0.939 _K(gl)YEMFAQTLQQSR_


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