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Query: CHMP2B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CHMP2B 0 2.640 -0.500 1.180

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CHMP2B Phosphorylation S199 0.711 0.812 _ATIS(ph)DEEIER_
CHMP2B Ubiquitylation K195 -0.063 _SLPSASTSK(gl)ATISDEEIER_

Background Information for CHMP2B:


Pubmed-CHMP2B »
Uniprot-CHMP2B »
Biogrid-CHMP2B »
ProteomicsDB-CHMP2B »

Tumorportal-CHMP2B »
COSMIC-CHMP2B »
GenomeRNAi-CHMP2B »
Genecards-CHMP2B


Protein-protein Interactions for CHMP2B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP6AP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait BUB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C1QBP Cat. description Hein, Mann, Cell 2015
Category members IP bait CD2AP Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP55 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait JUP Cat. description Hein, Mann, Cell 2015
Category members IP bait LTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH14 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP98 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAPSS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PTPN23 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB7A Cat. description Hein, Mann, Cell 2015
Category members IP bait RCC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SGOL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SPAST Cat. description Hein, Mann, Cell 2015
Category members IP bait TCEB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TEN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TIMELESS Cat. description Hein, Mann, Cell 2015
Category members IP bait TIPIN Cat. description Hein, Mann, Cell 2015
Category members IP bait TSG101 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS28 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS4B Cat. description Hein, Mann, Cell 2015


Protein Domains in CHMP2B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Snf7 IPR005024 0.58


Protein complexes (CORUM database) featuring CHMP2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1186 ESCRT-III complex Database 0.85


Categories featuring CHMP2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members GO Category GO:0016197 endosomal transport Database 0.43
Category members GO Category GO:0005622 intracellular Database 0.32
Category members Disease phenotype Amyotrophic_lateral_sclerosis Amyotrophic lateral sclerosis Database 0.21
Category members GO Category GO:0008219 cell death Database 0.08
Category members Pathway Pathway_800 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT 0 0.06
Category members Disease phenotype Behavioral_variant_of_frontotemporal_dementia Behavioral variant of frontotemporal dementia Database 0.04
Category members Disease phenotype Progressive_non-fluent_aphasia Progressive non-fluent aphasia Database 0.04
Category members Disease phenotype Semantic_dementia Semantic dementia Database 0.04
Category members GO Category GO:0031902 late endosome membrane Database 0


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