Results for the Category
REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI
(Pathway_953)
RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
W | |||||||
Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
---|---|---|---|---|---|---|---|---|
HMGB1 | 2 | -1.590 | 3.400 | 2.856 | -1.899 | 0.030 | -0.792 | |
NFKB2 | 0 | 1.750 | -0.820 | |||||
IKBKB | 0 | 0.400 | 0.610 | |||||
RIPK1 | 0 | -0.190 | 0.440 | |||||
APP | 0 | 0.100 | -0.260 | 0.285 | ||||
RELA | 0 | -1.130 | 1.600 | 0.793 | ||||
CHUK | 0 | -0.480 |
Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
---|---|---|---|---|---|
APP | Ubiquitylation | K751 | -1.778 | -1.280 | _HLSK(gl)M(ox)QQNGYENPTYK_ |
CHUK | Ubiquitylation | K296 | -1.637 | _GGPVDLTLK(gl)QPR_ | |
HMGB1 | Ubiquitylation | K50 | 0.651 | _WK(gl)TMSAK_ | |
HMGB1 | Ubiquitylation | K59 | 1.001 | 0.009 | _GK(gl)FEDMAK_ |
HMGB1 | Ubiquitylation | K114 | 0.314 | _IK(gl)GEHPGLSIGDVAK_ | |
HMGB1 | Ubiquitylation | K127 | 0.018 | _IKGEHPGLSIGDVAK(gl)K_ | |
HMGB1 | Ubiquitylation | K128 | -0.407 | _K(gl)LGEMWNNTAADDKQPYEK_ | |
HMGB1 | Ubiquitylation | K157 | 0.850 | _YEK(gl)DIAAYR_ | |
IKBKB | Ubiquitylation | K106 | 0.253 | _K(gl)YLNQFENCCGLR_ | |
IKBKB | Phosphorylation | S672 | 0.670 | 0.244 | _GPVSGS(ph)PDSMNASR_ |
NFKB2 | Ubiquitylation | K741 | -2.393 | _GHTPLDLTCSTK(gl)VK_ | |
NFKB2 | Ubiquitylation | K743 | -0.624 | _GHTPLDLTCSTKVK(gl)_ | |
RIPK1 | Ubiquitylation | K642 | -0.431 | _EGIK(gl)GATVGK_ |
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