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BIOCARTA_DREAM_PATHWAY
(Pathway_359)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
JUN 3 -0.930 0.930 -0.126
POLR2A 3 -0.397 0.863 1.593 -2.121 0.465
CREM 1 -0.880 2.870 -0.601 0.001
PRKAR1A 1 -0.550 0.230
PRKAR1A 1 -0.550 0.230
PRKAR1B 1 0.660 -0.470
PRKAR1B 1 0.660 -0.470
PRKAR2B 0 -0.290 0.380
MAPK3 0
PRKAR2A 0 -0.530 1.080 0.026 -1.317 -0.866 0.783 0.007
PRKAR2A 0 -0.530 1.080
CREB1 0 1.080 -0.800 -1.027
PRKACB 0 1.740 -1.200 -1.064
PRKACB 0 1.740 -1.200 -1.005 -0.697 0.234 0.487

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CREB1 Phosphorylation S271 -0.979 -1.450 _TAPTSTIAPGVVM(ox)ASS(ph)PALPTQPAEEAAR_
CREB1 Ubiquitylation K333 1.343 _ALK(gl)DLYCHK_
CREM Phosphorylation S464 0.128 _TTPSATSLPQTVVMTS(ph)PVTLTSQTTK_
CREM Ubiquitylation K481 -0.754 _TDDPQLK(gl)R_
CREM Ubiquitylation K505 0.609 0.811 _EYVK(gl)CLENR_
JUN Phosphorylation S58 -0.167 -1.247 _AKNS(ph)DLLTSPDVGLLK_
JUN Phosphorylation T62 2.545 1.674 _NSDLLT(ph)SPDVGLLK_
JUN Phosphorylation S63 2.030 1.458 _NSDLLTS(ph)PDVGLLK_
JUN Ubiquitylation K70 9.213 _NSDLLTSPDVGLLK(gl)_
JUN Phosphorylation S73 1.499 0.845 _LAS(ph)PELER_
JUN Phosphorylation S243 -0.642 -1.399 _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_
JUN Ubiquitylation K309 1.034 0.155 _EQVAQLK(gl)QK_
MAPK3 Phosphorylation Y204 -0.807 -2.487 _IADPEHDHTGFLTEY(ph)VATR_
MAPK3 Ubiquitylation K289 -0.608 _NYLQSLPSKTK(gl)_
POLR2A Ubiquitylation K32 1.006 _VQFGVLSPDELK(gl)R_
POLR2A Ubiquitylation K127 1.428 _IK(gl)DILAK_
POLR2A Ubiquitylation K132 0.487 _IKDILAK(gl)SK_
POLR2A Ubiquitylation K149 1.053 _LTHVYDLCK(gl)GK_
POLR2A Ubiquitylation K226 1.254 _VHEIFK(gl)R_
POLR2A Ubiquitylation K279 0.885 _NQDDLTHK(gl)LADIVK_
POLR2A Ubiquitylation K285 1.235 _LADIVK(gl)INNQLR_
POLR2A Ubiquitylation K417 0.662 _GNSQYPGAK(gl)YIIR_
POLR2A Ubiquitylation K707 1.333 _TYQDIQNTIK(gl)K_
POLR2A Ubiquitylation K710 1.362 1.417 _AK(gl)QDVIEVIEK_
POLR2A Ubiquitylation K751 -0.268 1.477 _DK(gl)TGSSAQK(gl)SLSEYNNFK_
POLR2A Ubiquitylation K758 -0.129 1.511 _DKTGSSAQK(gl)SLSEYNNFK_
POLR2A Ubiquitylation K767 1.702 _SLSEYNNFK(gl)SMVVSGAK_
POLR2A Ubiquitylation K775 1.252 _SMVVSGAK(gl)GSK_
POLR2A Ubiquitylation K812 -0.169 _TLPHFIK(gl)DDYGPESR_
POLR2A Ubiquitylation K976 0.145 0.332 _VIFPTGDSK(gl)VVLPCNLLR_
POLR2A Ubiquitylation K1014 0.766 _VVEGVK(gl)ELSK_
POLR2A Ubiquitylation K1125 4.356 1.173 _LK(gl)ELINISK_
POLR2A Ubiquitylation K1155 3.909 0.506 _AK(gl)DILCR_
POLR2A Ubiquitylation K1350 5.000 0.930 _VLSEK(gl)DVDPVR_
POLR2A Phosphorylation T1840 -1.940 _YT(ph)PTSPSYSPSSPEYTPTSPK_
POLR2A Phosphorylation T1842 -2.070 _YTPT(ph)SPSYS(ph)PSSPEYTPTSPK_
POLR2A Phosphorylation S1843 -1.841 -1.437 _YTPTS(ph)PSYSPSSPEYTPTSPK_
POLR2A Phosphorylation Y1846 -1.758 _YTPTSPSY(ph)SPSSPEYTPTS(ph)PK_
POLR2A Phosphorylation S1847 -1.016 -1.726 _Y(ph)TPTSPSYS(ph)PSSPEYTPT(ph)SPK_
POLR2A Phosphorylation S1849 -2.693 _YTPTSPSY(ph)SPS(ph)SPEYTPTSPK_
POLR2A Phosphorylation S1850 -1.360 -0.983 _YTPTSPSYSPSS(ph)PEYTPTS(ph)PK_
POLR2A Phosphorylation Y1853 -1.665 _YTPTSPSYSPSSPEY(ph)TPT(ph)SPK_
POLR2A Phosphorylation T1856 -1.740 _YTPTSPSYS(ph)PSSPEYTPT(ph)SPK_
POLR2A Phosphorylation S1857 -2.153 -2.282 _YTPTSPSYSPSSPEYTPTS(ph)PK_
POLR2A Phosphorylation T1877 -0.410 _YSPT(ph)SPTYS(ph)PTTPK_
POLR2A Phosphorylation S1878 -1.417 -0.623 _YSPTS(ph)PTYSPTT(ph)PK_
POLR2A Phosphorylation S1882 -0.491 0.086 _YSPTS(ph)PTYS(ph)PTTPK_
POLR2A Phosphorylation T1885 -0.372 -0.103 _YSPTS(ph)PTYSPTT(ph)PK_
POLR2A Phosphorylation S1889 -1.476 _YS(ph)PTSPTYSPTS(ph)PVYTPTSPK_
POLR2A Phosphorylation T1891 -3.041 -2.243 _YSPT(ph)SPTYSPTSPVYTPTSPK_
POLR2A Phosphorylation S1892 -2.675 -2.044 _YSPTS(ph)PTYSPTSPVYTPTSPK_
POLR2A Phosphorylation S1896 -1.174 _YSPTSPTYS(ph)PTSPVYTPT(ph)SPK_
POLR2A Phosphorylation T1898 -1.558 _YSPTS(ph)PTYSPT(ph)SPVYTPTSPK_
POLR2A Phosphorylation S1899 -0.903 -1.110 _YSPTSPTYSPTS(ph)PVYT(ph)PTSPK_
POLR2A Phosphorylation T1903 -0.180 -1.726 _YSPTSPTYSPTS(ph)PVYT(ph)PTSPK_
POLR2A Phosphorylation T1905 -1.328 -1.788 _YSPTSPTYSPTS(ph)PVYTPT(ph)SPK_
POLR2A Phosphorylation S1906 -2.720 -2.245 _YSPTS(ph)PTYSPTSPVYTPTS(ph)PK_
POLR2A Phosphorylation S1910 -1.108 -1.445 _YS(ph)PTSPTYS(ph)PTSPK_
POLR2A Phosphorylation T1912 -1.639 _YSPT(ph)SPTYS(ph)PTSPK_
POLR2A Phosphorylation S1913 -2.778 -1.508 _YSPTS(ph)PTYSPTS(ph)PK_
POLR2A Phosphorylation T1915 -2.612 _YSPTSPT(ph)YSPTSPK_
POLR2A Phosphorylation S1917 -2.286 -1.773 _YSPTS(ph)PTYS(ph)PTSPK_
POLR2A Phosphorylation T1919 -2.218 -1.471 _YSPTS(ph)PTYSPT(ph)SPK_
POLR2A Phosphorylation S1920 -1.088 -1.414 _YSPTS(ph)PTYSPTS(ph)PK_
PRKACB Ubiquitylation K30 -0.143 _AKEDFLKK(gl)_
PRKACB Ubiquitylation K93 0.839 0.714 _QIEHTLNEK(gl)R_
PRKACB Phosphorylation T243 -0.835 _T(ph)WTLCGTPEYLAPEIILSK_
PRKACB Phosphorylation T245 -0.116 -0.102 _TWT(ph)LCGTPEYLAPEIILSK_
PRKAR1A Ubiquitylation K63 -1.895 _LEKEEAK(gl)QIQNLQK_
PRKAR1A Ubiquitylation K70 -0.869 0.073 _QIQNLQK(gl)AGTR_
PRKAR1A Phosphorylation S83 -0.969 -0.776 _EDEIS(ph)PPPPNPVVK_
PRKAR1A Ubiquitylation K92 -3.269 -2.395 _TDSREDEISPPPPNPVVK(gl)GR_
PRKAR1A Ubiquitylation K222 0.412 0.536 _TNVK(gl)LWGIDR_
PRKAR1A Ubiquitylation K244 -0.384 3.721 _K(gl)MYEEFLSK_
PRKAR1A Ubiquitylation K261 -0.886 _VSILESLDK(gl)WER_
PRKAR1A Ubiquitylation K346 0.329 _GPLK(gl)CVK_
PRKAR1A Ubiquitylation K349 -0.425 -0.103 _CVK(gl)LDRPR_
PRKAR1A Ubiquitylation K367 -0.939 0.044 _VLGPCSDILK(gl)R_
PRKAR1B Phosphorylation S3 0.185 0.343 _(ac)AS(ph)PPACPSEEDESLKGCELYVQLHGIQQVLK_
PRKAR1B Ubiquitylation K244 -0.384 3.721 _K(gl)MYEEFLSK_
PRKAR1B Ubiquitylation K346 0.329 _GPLK(gl)CVK_
PRKAR1B Ubiquitylation K349 -0.425 -0.103 _CVK(gl)LDRPR_
PRKAR2A Phosphorylation S99 0.020 0.056 _RVS(ph)VCAETYNPDEEEEDTDPR_
PRKAR2A Phosphorylation T104 -0.175 _RVSVCAET(ph)YNPDEEEEDTDPR_
PRKAR2A Ubiquitylation K359 0.640 _GQYFGELALVTNK(gl)PR_
PRKAR2B Phosphorylation T69 -0.367 _TWGDLGAAAGGGT(ph)PSK_
PRKAR2B Phosphorylation S114 0.366 0.525 _RAS(ph)VCAEAYNPDEEEDDAESR_
PRKAR2B Ubiquitylation K359 0.640 _GQYFGELALVTNK(gl)PR_


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