RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
W

Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
INSR	2	-0.850	0.830				1.143	0.785
MAPK3	0
GRB10	0	0.900	-0.860
SOS1	0	0.500	-0.620	-0.570
CRK	0	-0.790	0.230
IRS1	0
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
IRS2	0	-0.190	-0.130

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
CRK	Phosphorylation	S40	0.533	0.363	_DS(ph)STSPGDYVLSVSENSR_
CRK	Phosphorylation	S41	1.065	0.801	_DSS(ph)TSPGDYVLSVSENSR_
GRB10	Phosphorylation	S104	-0.985	-0.688	_SIQPQVS(ph)PR_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
INSR	Ubiquitylation	K1022	-0.603		_EK(gl)ITLLR_
INSR	Ubiquitylation	K1047	0.305	0.711	_DIIK(gl)GEAETR_
INSR	Ubiquitylation	K1057	0.482	0.484	_VAVK(gl)TVNESASLR_
INSR	Ubiquitylation	K1352	1.606	2.754	_DGGSSLGFK(gl)R_
IRS1	Phosphorylation	S1101	-0.078		_HSS(ph)ETFSSTPSATR_
IRS2	Phosphorylation	S308	-0.079	-0.510	_SKS(ph)QSSGSSATHPISVPGAR_
IRS2	Phosphorylation	T365	0.641	0.852	_T(ph)ASEGDGGAAAGAAAAGAR_
IRS2	Phosphorylation	S367	0.757	0.612	_TAS(ph)EGDGGAAAGAAAAGAR_
IRS2	Phosphorylation	S393	-1.580	-1.221	_PVSVAGSPLS(ph)PGPVR_
IRS2	Phosphorylation	S520	0.359	-1.006	_S(ph)NTPESIAETPPAR_
IRS2	Phosphorylation	T522	-1.103	-0.770	_SNT(ph)PESIAETPPAR_
IRS2	Phosphorylation	T529	0.230	0.164	_S(ph)NTPESIAET(ph)PPAR_
IRS2	Phosphorylation	S562	-0.026	0.439	_RVS(ph)GDAAQDLDR_
IRS2	Phosphorylation	S579	0.542	0.362	_RTYS(ph)LTTPAR_
IRS2	Phosphorylation	S621		-0.190	_LCPSCPAS(ph)SPK_
IRS2	Phosphorylation	S622	-0.195		_LCPSCPASS(ph)PK_
IRS2	Phosphorylation	S681	0.409		_SDDYM(ox)PM(ox)S(ph)PASVSAPK_
IRS2	Phosphorylation	S732	-1.089		_AS(ph)SPAESSPEDSGYM(ox)R_
IRS2	Phosphorylation	S733	-1.027	0.522	_ASS(ph)PAESSPEDSGYM(ox)R_
IRS2	Phosphorylation	S738		0.522	_ASS(ph)PAESS(ph)PEDSGYMR_
IRS2	Phosphorylation	S917	-0.592	-1.025	_S(ph)PGEYINIDFGEPGAR_
IRS2	Phosphorylation	S1164		-0.499	_HSSETFSSTTTVTPVS(ph)PSFAHNPK_
IRS2	Phosphorylation	S1178	0.766	0.277	_HNSAS(ph)VENVSLR_
IRS2	Phosphorylation	T1204		-0.454	_SSEGGVGVGPGGGDEPPT(ph)SPR_
IRS2	Phosphorylation	S1205	-0.291		_SSEGGVGVGPGGGDEPPTS(ph)PR_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_