Results for the Category
negative regulation of telomerase activity
(GO:0051974)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| PIF1 | 1 | 0.190 | 0.090 | |||||
| PML | 1 | -0.420 | 0.350 | -0.244 | 0.322 | |||
| POT1 | 0 | 0.280 | -0.550 | |||||
| MEN1 | 0 | 1.080 | -1.150 | 0.101 | 0.684 | -0.063 | ||
| MEN1 | 0 | 1.080 | -1.150 | 0.395 | ||||
| MEN1 | 0 | 1.080 | -1.150 | |||||
| TERF1 | 0 | -1.080 | 1.620 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| MEN1 | Ubiquitylation | K8 | -1.132 | 0.088 | _AAQK(gl)TLFPLR_ |
| MEN1 | Phosphorylation | S218 | -0.820 | _RES(ph)KPEEPPPPK_ | |
| PIF1 | Phosphorylation | S151 | 4.353 | _DFVTIS(ph)PVQPEER_ | |
| PML | Ubiquitylation | K394 | 0.515 | 0.360 | _LQDLSSCITQGK(gl)DAAVSKK_ |
| PML | Phosphorylation | S403 | 3.141 | _KAS(ph)PEAASTPRDPIDVDLPEEAER_ | |
| PML | Ubiquitylation | K476 | -0.403 | -0.735 | _GPSYGEDVSNTTTAQK(gl)R_ |
| PML | Phosphorylation | S504 | -0.198 | -0.109 | _S(ph)SPEQPRPSTSK_ |
| PML | Phosphorylation | S505 | -0.198 | -0.109 | _S(ph)SPEQPRPSTSK_ |
| PML | Phosphorylation | S518 | -1.632 | -1.605 | _AVS(ph)PPHLDGPPS(ph)PR_ |
| PML | Phosphorylation | S527 | -1.392 | -1.605 | _AVS(ph)PPHLDGPPS(ph)PR_ |
| PML | Phosphorylation | S530 | 0.466 | 0.093 | _S(ph)PVIGSEVFLPNSNHVASGAGEAEER_ |
| PML | Ubiquitylation | K623 | -0.784 | _IDNETQK(gl)ISQLAAVNR_ | |
| POT1 | Ubiquitylation | K469 | -1.327 | _LSNK(gl)FNSVIPVR_ | |
| TERF1 | Phosphorylation | S11 | -0.248 | -0.254 | _(ac)AEDVSSAAPS(ph)PR_ |
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