Results for the Category
BH3 domain binding
(GO:0051434)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| BAX | 0 | 1.590 | -1.170 | 0.811 | 0.359 | |||
| MCL1 | 0 | 1.740 | -0.780 | -0.419 | ||||
| BCL2L1 | 0 | |||||||
| BCL2 | 0 | 0.910 | -0.740 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| BAX | Ubiquitylation | K57 | -1.174 | _MGGEAPELALDPVPQDASTK(gl)K_ | |
| BAX | Ubiquitylation | K58 | -1.718 | -1.174 | _MGGEAPELALDPVPQDASTKK(gl)_ |
| BAX | Ubiquitylation | K64 | 0.708 | 1.306 | _LSECLK(gl)R_ |
| BCL2 | Ubiquitylation | K22 | 1.480 | _YIHYK(gl)LSQR_ | |
| BCL2L1 | Ubiquitylation | K87 | 0.026 | _EVIPMAAVK(gl)QALR_ | |
| MCL1 | Ubiquitylation | K40 | -0.321 | _LLATEK(gl)EASAR_ | |
| MCL1 | Phosphorylation | T163 | -1.997 | -1.027 | _RPAVLPLLELVGESGNNTSTDGSLPST(ph)PPPAEEEEDELYR_ |
| MCL1 | Ubiquitylation | K194 | -1.646 | -1.025 | _EQATGAK(gl)DTK(gl)PMGR_ |
| MCL1 | Ubiquitylation | K197 | -1.782 | -1.165 | _EQATGAK(gl)DTK(gl)PMGR_ |
| MCL1 | Ubiquitylation | K308 | -0.687 | 0.011 | _DWLVK(gl)QR_ |
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