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positive regulation of Notch signaling pathway
(GO:0045747)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
SLC35C2 0 -1.250 2.100
JAG1 0 -0.260 0.070
EYA1 0 -0.440 -0.140
HES1 0 -0.940 0.860
AAK1 0 1.900 -1.150
AAK1 0 1.900 -1.150 0.289 -0.421
STAT3 0 0.200 -1.270 0.334
SOX2 0 -0.250 0.870

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AAK1 Phosphorylation T605 -0.689 _VQT(ph)TPPPAVQGQK_
AAK1 Phosphorylation T606 -0.648 -1.206 _VQTT(ph)PPPAVQGQK_
AAK1 Phosphorylation T620 -0.540 -0.524 _VGSLT(ph)PPSS(ph)PK_
AAK1 Phosphorylation S623 -0.540 -0.550 _VGSLT(ph)PPS(ph)SPK_
AAK1 Phosphorylation S624 -0.737 -0.516 _VGSLT(ph)PPSS(ph)PK_
AAK1 Phosphorylation S652 0.769 1.397 _S(ph)TQLLQAAAAEASLNK_
AAK1 Phosphorylation T653 0.769 1.397 _S(ph)TQLLQAAAAEASLNK_
AAK1 Phosphorylation S947 -0.044 0.120 _S(ph)ESNEDLFGLVPFDEITGSQQQK_
AAK1 Phosphorylation S949 0.168 -0.189 _SES(ph)NEDLFGLVPFDEITGSQQQK_
AAK1 Phosphorylation T1014 -0.576 0.108 _TLKPTYRT(ph)PER_
EYA1 Ubiquitylation K513 -0.108 _NNVGGLLGPAK(gl)R_
EYA1 Ubiquitylation K587 -1.219 _IGK(gl)ESCFER_
HES1 Ubiquitylation K66 0.212 _TLILDALK(gl)K_
HES1 Ubiquitylation K67 0.212 _TLILDALK(gl)K_
HES1 Ubiquitylation K109 -0.891 _AQMTAALSTDPSVLGK(gl)YR_
JAG1 Ubiquitylation K1142 -0.783 _HGANTVPIKDYENK(gl)_
SLC35C2 Phosphorylation S364 0.599 0.693 _GLGS(ph)SPDLELLLR_
SLC35C2 Phosphorylation S365 0.483 _GLGS(ph)SPDLELLLR_
SOX2 Phosphorylation S251 0.157 -0.109 _SEASSS(ph)PPVVTSSSHSR_
STAT3 Ubiquitylation K177 0.957 _VVENLQDDFDFNYK(gl)TLK_
STAT3 Ubiquitylation K180 1.179 _TLK(gl)SQGDMQDLNGNNQSVTR_
STAT3 Ubiquitylation K244 0.262 _TLTDEELADWK(gl)R_
STAT3 Phosphorylation T714 -0.338 _FICVT(ph)PTTCSNTIDLPMS(ph)PR_
STAT3 Phosphorylation S727 -0.079 0.156 _FICVTPTTCSNTIDLPMS(ph)PR_


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