Results for the Category
regulation of transcription from RNA polymerase II promoter in response to oxidative stress
(GO:0043619)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| HMOX1 | 0 | 0.330 | 0.220 | -1.817 | -1.289 | |||
| HIF1A | 0 | -0.480 | 0.400 | |||||
| ARNT | 0 | 1.120 | -0.500 | |||||
| SIN3A | 0 | -0.610 | 0.780 | 0.378 | -0.208 | 0.304 | -0.168 | 0.410 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ARNT | Phosphorylation | S81 | 1.133 | _FARS(ph)DDEQSSADKER_ | |
| ARNT | Ubiquitylation | K421 | -2.502 | _DSFQQVVK(gl)LK_ | |
| HIF1A | Ubiquitylation | K10 | -1.686 | _(ac)MEGAGGANDK(gl)K_ | |
| HIF1A | Ubiquitylation | K11 | -1.686 | _(ac)MEGAGGANDK(gl)K_ | |
| HIF1A | Ubiquitylation | K173 | -0.662 | _MK(gl)CTLTSR_ | |
| HIF1A | Ubiquitylation | K186 | -0.590 | _TMNIK(gl)SATWK_ | |
| HIF1A | Ubiquitylation | K252 | -0.784 | _HSLDM(ox)K(gl)FSYCDER_ | |
| HIF1A | Ubiquitylation | K371 | -0.508 | _PVESSDMK(gl)MTQLFTK_ | |
| HIF1A | Ubiquitylation | K378 | -0.077 | _MTQLFTK(gl)VESEDTSSLFDK_ | |
| HIF1A | Ubiquitylation | K390 | -0.348 | _VESEDTSSLFDK(gl)LKK_ | |
| HIF1A | Ubiquitylation | K392 | -0.546 | _VESEDTSSLFDKLK(gl)_ | |
| HIF1A | Ubiquitylation | K393 | -0.451 | _VESEDTSSLFDKLKK(gl)_ | |
| HIF1A | Ubiquitylation | K710 | -1.696 | _TTVPEEELNPK(gl)ILALQNAQR_ | |
| HMOX1 | Ubiquitylation | K243 | -0.972 | _ASNK(gl)VQDSAPVETPR_ | |
| HMOX1 | Ubiquitylation | K256 | -1.769 | _GK(gl)PPLNTR_ | |
| SIN3A | Ubiquitylation | K155 | 0.182 | _EFK(gl)SQSIDTPGVISR_ | |
| SIN3A | Phosphorylation | T266 | -0.572 | _VSKPSQLQAHTPASQQT(ph)PPLPPYASPR_ | |
| SIN3A | Phosphorylation | S277 | -1.598 | _S(ph)PPVQPHTPVTISLGTAPSLQNNQPVEFNHAINYVNK_ | |
| SIN3A | Phosphorylation | S295 | -1.959 | _SPPVQPHTPVTISLGTAPS(ph)LQNNQPVEFNHAINYVNK_ | |
| SIN3A | Ubiquitylation | K638 | -0.223 | _VLEAIQK(gl)K_ | |
| SIN3A | Ubiquitylation | K639 | -0.223 | _VLEAIQK(gl)K_ | |
| SIN3A | Ubiquitylation | K715 | 1.012 | _GFNK(gl)VWR_ | |
| SIN3A | Phosphorylation | S832 | 0.764 | 0.363 | _GDLS(ph)DVEEEEEEEM(ox)DVDEATGAVKK_ |
| SIN3A | Ubiquitylation | K875 | 0.131 | 0.003 | _LLFSNTAAQK(gl)LR_ |
| SIN3A | Ubiquitylation | K937 | -0.224 | -0.025 | _DK(gl)SDSPAIQLR_ |
| SIN3A | Phosphorylation | S940 | -0.107 | _DKSDS(ph)PAIQLR_ | |
| SIN3A | Phosphorylation | T1111 | 0.691 | 0.517 | _YM(ox)NSDTT(ph)SPELR_ |
| SIN3A | Phosphorylation | S1112 | 0.623 | 0.725 | _YM(ox)NSDTTS(ph)PELR_ |
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