Results for the Category
positive regulation of phosphatidylinositol 3-kinase activity
(GO:0043552)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| LYN | 1 | -1.790 | 3.770 | |||||
| LYN | 1 | -1.790 | 3.770 | |||||
| FGFR3 | 0 | -1.120 | 1.390 | |||||
| CDC42 | 0 | -0.170 | 0.490 | -0.597 | -1.527 | -1.013 | ||
| CDC42 | 0 | 1.240 | -0.940 | -0.597 | -1.527 | -1.013 | ||
| FLT1 | 0 | -1.240 | 1.900 | |||||
| TGFB1 | 0 | -0.550 | 1.050 | |||||
| RAC1 | 0 | -0.580 | 1.580 | 0.486 | -0.364 | -0.568 | ||
| IRS1 | 0 | |||||||
| ERBB4 | 0 | |||||||
| ERBB4 | 0 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| CDC42 | Ubiquitylation | K173 | -1.839 | _DDPSTIEK(gl)LAK_ | |
| CDC42 | Ubiquitylation | K178 | -0.801 | -0.716 | _NK(gl)QKPITPETAEK_ |
| CDC42 | Ubiquitylation | K180 | -1.806 | _QK(gl)PITPETAEK(gl)LAR_ | |
| CDC42 | Ubiquitylation | K189 | -1.082 | _QKPITPETAEK(gl)LAR_ | |
| CDC42 | Ubiquitylation | K198 | 0.550 | 1.159 | _AVK(gl)YVECSALTQK_ |
| CDC42 | Ubiquitylation | K208 | -0.937 | 0.038 | _YVECSALTQK(gl)GLK_ |
| CDC42 | Ubiquitylation | K228 | -2.488 | _NVFDEAILAALEPPEPK(gl)K_ | |
| CDC42 | Ubiquitylation | K229 | -1.254 | _NVFDEAILAALEPPEPKK(gl)_ | |
| ERBB4 | Ubiquitylation | K714 | 0.078 | _ILK(gl)ETELKR_ | |
| ERBB4 | Ubiquitylation | K745 | -0.474 | 0.342 | _GIWVPEGETVK(gl)IPVAIK_ |
| ERBB4 | Ubiquitylation | K854 | -0.859 | _NVLVK(gl)SPNHVK_ | |
| FGFR3 | Ubiquitylation | K205 | -0.115 | _IGGIK(gl)LR_ | |
| FLT1 | Ubiquitylation | K953 | -1.081 | _MEPGLEQGK(gl)KPR_ | |
| IRS1 | Phosphorylation | S1101 | -0.078 | _HSS(ph)ETFSSTPSATR_ | |
| LYN | Ubiquitylation | K20 | -0.592 | _GKDSLSDDGVDLK(gl)TQPVR_ | |
| LYN | Ubiquitylation | K40 | 0.100 | _DPTSNK(gl)QQRPVPESQLLPGQR_ | |
| LYN | Phosphorylation | S104 | 0.944 | 0.841 | _DSLS(ph)DDGVDLK_ |
| LYN | Ubiquitylation | K213 | 0.441 | _HYQK(gl)QADGLCR_ | |
| LYN | Ubiquitylation | K477 | -0.191 | _VENCPDELYDIMK(gl)MCWK_ | |
| RAC1 | Ubiquitylation | K115 | -1.745 | -0.215 | _AK(gl)WYPEVR_ |
| RAC1 | Ubiquitylation | K142 | 0.492 | _LDLRDDK(gl)DTIEK_ | |
| RAC1 | Ubiquitylation | K152 | 0.099 | -0.292 | _K(gl)LTPITYPQGLAMAK_ |
| RAC1 | Ubiquitylation | K166 | -0.981 | -0.655 | _LTPITYPQGLAMAK(gl)EIGAVK_ |
| RAC1 | Ubiquitylation | K172 | 1.026 | 0.412 | _EIGAVK(gl)YLECSALTQR_ |
| RAC1 | Ubiquitylation | K185 | -0.113 | 0.578 | _GLK(gl)TVFDEAIR_ |
| RAC1 | Ubiquitylation | K202 | -1.379 | -1.447 | _AVLCPPPVK(gl)KR_ |
| RAC1 | Ubiquitylation | K203 | -1.708 | -1.447 | _AVLCPPPVKK(gl)_ |
| TGFB1 | Ubiquitylation | K50 | -0.557 | _GQILSK(gl)LR_ |
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