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nuclear lamina
(GO:0005652)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
NARF 1 -0.640 2.460
CASK 1 2.050 -1.110
CASK 1 2.050 -1.110 -0.162 -0.217 -0.918 0.048 0.372
HLCS 1 -1.940 3.470
LMNA 1 0.760 -0.400 1.025 -0.121 0.091 1.281 0.818
LMNB2 0 -0.480 -0.180 0.912 1.309 0.829

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CASK Ubiquitylation K41 1.029 1.231 _ETGQQFAVK(gl)IVDVAK_
CASK Ubiquitylation K60 0.240 0.541 _FTSSPGLSTEDLK(gl)R_
CASK Phosphorylation S570 0.125 _TQSS(ph)SCEDLPSTTQPK_
CASK Phosphorylation S571 0.134 -0.032 _TQSSS(ph)CEDLPSTTQPK_
CASK Ubiquitylation K665 -0.631 _LENSK(gl)NGTAGLIPSPELQEWR_
CASK Ubiquitylation K691 1.108 _TK(gl)QEQQASCTWFGK_
CASK Ubiquitylation K703 0.627 _TKQEQQASCTWFGK(gl)K_
CASK Ubiquitylation K704 0.627 _TKQEQQASCTWFGK(gl)K_
HLCS Phosphorylation S124 -0.164 -0.488 _FAS(ph)AENIPDLPYDYSSSLESVADETSPER_
HLCS Phosphorylation S147 -0.852 -0.599 _FASAENIPDLPYDYSSSLESVADETS(ph)PER_
LMNA Phosphorylation T19 -1.262 _SGAQASST(ph)PLS(ph)PTR_
LMNA Phosphorylation S22 -0.433 0.377 _SGAQASST(ph)PLS(ph)PTR_
LMNA Ubiquitylation K32 0.054 _LQEK(gl)EDLQELNDR_
LMNA Ubiquitylation K78 -0.306 _EVSGIK(gl)AAYEAELGDAR_
LMNA Ubiquitylation K97 0.499 -0.167 _TLDSVAK(gl)ER_
LMNA Ubiquitylation K108 0.586 _LQLELSK(gl)VR_
LMNA Ubiquitylation K114 0.753 _VREEFK(gl)ELK_
LMNA Ubiquitylation K117 0.571 _VREEFKELK(gl)AR_
LMNA Ubiquitylation K122 0.401 _NTK(gl)KEGDLIAAQAR_
LMNA Ubiquitylation K123 0.401 _NTK(gl)KEGDLIAAQAR_
LMNA Ubiquitylation K135 0.856 1.129 _LK(gl)DLEALLNSK_
LMNA Ubiquitylation K155 -0.218 0.375 _EAALSTALSEK(gl)R_
LMNA Ubiquitylation K171 0.656 0.450 _GQVAK(gl)LEAALGEAKK_
LMNA Ubiquitylation K180 0.977 0.753 _LEAALGEAK(gl)K_
LMNA Ubiquitylation K181 0.458 0.679 _K(gl)QLQDEMLR_
LMNA Ubiquitylation K219 0.784 0.456 _NIYSEELRETK(gl)R_
LMNA Ubiquitylation K233 0.194 1.930 _LVEIDNGK(gl)QREFESR_
LMNA Ubiquitylation K261 0.576 _AQHEDQVEQYKK(gl)ELEK_
LMNA Ubiquitylation K265 0.532 0.714 _ELEK(gl)TYSAK_
LMNA Ubiquitylation K270 0.362 0.777 _TYSAK(gl)LDNAR_
LMNA Ubiquitylation K311 0.853 0.977 _IDSLSAQLSQLQK(gl)QLAAK_
LMNA Ubiquitylation K378 -0.030 0.701 _K(gl)LLEGEEER_
LMNA Phosphorylation S390 -0.020 -0.112 _LRLS(ph)PSPTSQR_
LMNA Phosphorylation S392 -0.062 -0.026 _LSPS(ph)PTSQR_
LMNA Phosphorylation S403 0.641 _GRAS(ph)SHSSQTQGGGSVTK_
LMNA Phosphorylation S458 0.520 _NKS(ph)NEDQSMGNWQIK_
LMNA Phosphorylation S632 0.730 _SVGGS(ph)GGGSFGDNLVTR_
LMNA Phosphorylation S636 0.537 1.498 _SVGGSGGGS(ph)FGDNLVTR_
LMNB2 Phosphorylation T14 -1.256 _AGGPAT(ph)PLS(ph)PTR_
LMNB2 Phosphorylation S17 -1.177 -0.088 _AGGPAT(ph)PLS(ph)PTR_
LMNB2 Ubiquitylation K61 0.704 0.753 _ISEK(gl)EEVTTR_
LMNB2 Ubiquitylation K103 0.917 1.128 _LQIEIGK(gl)LR_
LMNB2 Ubiquitylation K113 0.396 _AELDEVNK(gl)SAK_
LMNB2 Ubiquitylation K116 0.462 _AELDEVNKSAK(gl)_
LMNB2 Ubiquitylation K166 0.693 0.289 _AQLAK(gl)AEDGHAVAK_
LMNB2 Ubiquitylation K180 0.751 _QLEK(gl)ETLMR_
LMNB2 Ubiquitylation K265 0.078 1.270 _LELEQTYQAK(gl)LDSAK_
LMNB2 Ubiquitylation K270 -0.086 -0.261 _LDSAK(gl)LSSDQNDKAASAAR_
LMNB2 Ubiquitylation K278 0.240 0.830 _LSSDQNDK(gl)AASAAR_
LMNB2 Ubiquitylation K288 0.800 1.300 _EELK(gl)EAR_
LMNB2 Phosphorylation S399 1.142 0.767 _ATS(ph)SSSGSLSATGR_
LMNB2 Phosphorylation S400 1.015 0.953 _ATSS(ph)SSGSLSATGR_
LMNB2 Phosphorylation S402 1.194 _ATSSSS(ph)GSLSATGR_
LMNB2 Phosphorylation S404 1.103 _ATSSSSGS(ph)LSATGR_
LMNB2 Phosphorylation S406 0.617 _ATSSSSGSLS(ph)ATGR_
LMNB2 Ubiquitylation K474 0.084 _NNSDK(gl)DQSLGNWR_
LMNB2 Phosphorylation T498 0.866 _RQVLEGEEIAYKFT(ph)PK_
LMNB2 Ubiquitylation K500 0.029 0.094 _FTPK(gl)YILR_
NARF Ubiquitylation K441 2.444 _GQAQTPDGHADK(gl)ALLR_


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