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COFFIN-SIRIS SYNDROME
(COFFIN-SIRIS_SYNDROME)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
SMARCB1 1 0.850 -0.060 0.041 -0.003 0.699 0.354 -0.731
SMARCB1 1 0.850 -0.060 0.738 1.594
ARID1A 1 0.360 -0.350 0.683 0.272 0.870 -0.131 0.043
ARID1B 0 1.330 -0.340 0.410 -0.553 0.164 0.200
SMARCE1 0 -0.270 0.280 0.341
SMARCE1 0 -0.270 0.280 0.251 0.796 0.284 0.349
SMARCA4 0 -0.810 1.520 0.629 -0.158 0.141 0.337 0.333

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ARID1A Phosphorylation S363 0.211 0.022 _SHHAPM(ox)S(ph)PGSSGGGGQPLAR_
ARID1A Phosphorylation S367 -0.142 _SHHAPMSPGSS(ph)GGGGQPLAR_
ARID1A Phosphorylation S381 0.335 _TPQPS(ph)SPMDQMGK_
ARID1A Phosphorylation S382 1.506 0.780 _TPQPSS(ph)PMDQMGK_
ARID1A Phosphorylation S696 -0.934 -0.737 _GPS(ph)PSPVGSPASVAQSR_
ARID1A Phosphorylation S702 0.267 -0.175 _GPS(ph)PSPVGS(ph)PASVAQSR_
ARID1A Phosphorylation S705 0.157 _GPS(ph)PSPVGSPAS(ph)VAQSR_
ARID1A Phosphorylation S772 -0.112 -0.485 _NPQMPQYSSPQPGSALS(ph)PR_
ARID1A Phosphorylation S1182 1.584 1.063 _S(ph)NSVGIQDAFNDGSDSTFQK_
ARID1A Phosphorylation S1184 1.732 1.114 _SNS(ph)VGIQDAFNDGSDSTFQK_
ARID1A Phosphorylation S1754 0.131 -0.654 _VS(ph)SPAPM(ox)EGGEEEEELLGPK_
ARID1A Phosphorylation S1755 -0.409 -0.587 _VSS(ph)PAPMEGGEEEEELLGPK_
ARID1A Phosphorylation S1944 -0.489 _FPFGIS(ph)PAQSHR_
ARID1B Phosphorylation S1555 -0.906 _MS(ph)PSKSPFLPSMK_
SMARCA4 Ubiquitylation K357 -0.934 _ITPIQK(gl)PR_
SMARCA4 Ubiquitylation K405 0.109 1.148 _ATIELK(gl)ALR_
SMARCA4 Ubiquitylation K437 -0.317 _DTALETALNAK(gl)AYKR_
SMARCA4 Ubiquitylation K455 0.225 _ITEK(gl)LEK_
SMARCA4 Ubiquitylation K496 0.923 _SVTGK(gl)IQK_
SMARCA4 Phosphorylation S677 -0.880 -0.324 _KAENAEGQTPAIGPDGEPLDETSQMS(ph)DLPVK_
SMARCA4 Ubiquitylation K1283 0.125 _ILAAAK(gl)YK_
SMARCA4 Phosphorylation S1413 -0.265 0.515 _EVDYSDS(ph)LTEK_
SMARCA4 Phosphorylation S1486 -0.713 -0.935 _LS(ph)PNPPNLTK_
SMARCB1 Ubiquitylation K13 0.411 -0.949 _TFGQK(gl)PVK_
SMARCB1 Ubiquitylation K208 -0.170 _LDMEIDGQK(gl)LR_
SMARCE1 Ubiquitylation K92 0.706 _ASNPDLK(gl)LWEIGK_
SMARCE1 Ubiquitylation K271 -0.418 -0.010 _FLESTDSFNNELK(gl)R_


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