Results for the Category
TNF-alpha/Nf-kappa B signaling complex (RPL6, RPL30, RPS13, CHUK, DDX3X, NFKB2, NFKBIB, REL, IKBKG, NFKB1, MAP3K8, RELB, GLG1, NFKBIA, RELA, TNIP2, GTF2I)
(5232)

RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
W

Protein Results:
Results for post-translational modifications (below)

Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
RPL6	2	-0.910	1.320	0.056	-0.616	0.395	-0.617	-0.229
RPS13	2	-0.240	1.210	-0.179	0.154	-0.146	-0.498	-0.115
RPL30	2	-1.210	2.130	1.223	-0.212	0.342	-0.220	0.078
DDX3X	2	-0.250	0.370	0.081	-0.794	-0.166	-0.062	-0.025
GTF2IRD2	1	0.070	-0.050	-0.275	-0.199	0.020	0.150	0.028
GTF2IRD2B	1			-0.275	-0.199	0.020	0.150	0.028
IKBKG	0
NFKB2	0	1.750	-0.820
GLG1	0	-0.920	0.880		-0.614	-0.283	0.926	0.784
NFKB1	0	0.720	-0.810
RELA	0	-1.130	1.600	0.793
CHUK	0			-0.480

PTM Sites:
Back to Protein Results

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
CHUK	Ubiquitylation	K296		-1.637	_GGPVDLTLK(gl)QPR_
DDX3X	Ubiquitylation	K78	1.311		_DK(gl)DAYSSFGSR_
DDX3X	Ubiquitylation	K93	0.657	1.846	_GK(gl)SSFFSDR_
DDX3X	Phosphorylation	S94	0.172		_S(ph)SFFSDRGSGSR_
DDX3X	Phosphorylation	S102	0.008	0.230	_SSFFSDRGS(ph)GSR_
DDX3X	Phosphorylation	S104	-0.231	0.320	_SSFFSDRGSGS(ph)R_
DDX3X	Ubiquitylation	K130	1.572	1.502	_SGFGK(gl)FER_
DDX3X	Ubiquitylation	K347	-0.406	0.360	_GK(gl)IGLDFCK_
DDX3X	Ubiquitylation	K503	-0.796		_SGK(gl)SPILVATAVAAR_
DDX3X	Phosphorylation	S602		-0.349	_S(ph)SRFSGGFGAR_
DDX3X	Phosphorylation	S603		-0.330	_SS(ph)RFSGGFGAR_
DDX3X	Phosphorylation	S606	-0.248	-0.447	_FS(ph)GGFGAR_
GTF2IRD2	Phosphorylation	S16	0.584	0.164	_(ac)AQVAMSTLPVEDEES(ph)SESR_
GTF2IRD2	Phosphorylation	S17	0.428	0.049	_(ac)AQVAM(ox)STLPVEDEESS(ph)ESR_
GTF2IRD2	Phosphorylation	S19		0.274	_(ac)AQVAMSTLPVEDEESSES(ph)R_
GTF2IRD2	Ubiquitylation	K74	0.301	0.254	_DFQK(gl)DFVK_
GTF2IRD2	Ubiquitylation	K130	-0.741	-0.548	_ALGK(gl)STVVPVPYEK_
GTF2IRD2	Phosphorylation	S210	-0.322	-0.436	_SILS(ph)PGGSCGPIK_
GTF2IRD2	Ubiquitylation	K353	0.303	-1.178	_EFNFEK(gl)WNAR_
GTF2IRD2	Ubiquitylation	K378	0.347		_KYAQAIK(gl)AK_
GTF2IRD2	Phosphorylation	S412	1.989	0.874	_RPS(ph)TYGIPR_
GTF2IRD2	Phosphorylation	S515		-0.502	_FEAHPNDLYVEGLPENIPFRS(ph)PSWYGIPR_
GTF2IRD2	Phosphorylation	T556	-0.743	-0.549	_T(ph)NTPVKEDWNVR_
GTF2IRD2	Phosphorylation	T558	0.025	-0.496	_TNT(ph)PVKEDWNVR_
GTF2IRD2	Ubiquitylation	K561	0.309	-0.904	_TNTPVK(gl)EDWNVR_
GTF2IRD2	Ubiquitylation	K752	-0.663		_CGEALGLK(gl)QAVK_
GTF2IRD2	Phosphorylation	S830	1.307		_KINS(ph)SPNVNTTASGVEDLNIIQVTIPDDDNER_
GTF2IRD2B	Phosphorylation	S16	0.584	0.164	_(ac)AQVAMSTLPVEDEES(ph)SESR_
GTF2IRD2B	Phosphorylation	S17	0.428	0.049	_(ac)AQVAM(ox)STLPVEDEESS(ph)ESR_
GTF2IRD2B	Phosphorylation	S19		0.274	_(ac)AQVAMSTLPVEDEESSES(ph)R_
GTF2IRD2B	Ubiquitylation	K74	0.301	0.254	_DFQK(gl)DFVK_
GTF2IRD2B	Ubiquitylation	K130	-0.741	-0.548	_ALGK(gl)STVVPVPYEK_
GTF2IRD2B	Phosphorylation	S210	-0.322	-0.436	_SILS(ph)PGGSCGPIK_
GTF2IRD2B	Ubiquitylation	K353	0.303	-1.178	_EFNFEK(gl)WNAR_
GTF2IRD2B	Ubiquitylation	K378	0.347		_KYAQAIK(gl)AK_
GTF2IRD2B	Phosphorylation	S412	1.989	0.874	_RPS(ph)TYGIPR_
GTF2IRD2B	Phosphorylation	S515		-0.502	_FEAHPNDLYVEGLPENIPFRS(ph)PSWYGIPR_
GTF2IRD2B	Phosphorylation	T556	-0.743	-0.549	_T(ph)NTPVKEDWNVR_
GTF2IRD2B	Phosphorylation	T558	0.025	-0.496	_TNT(ph)PVKEDWNVR_
GTF2IRD2B	Ubiquitylation	K561	0.309	-0.904	_TNTPVK(gl)EDWNVR_
GTF2IRD2B	Ubiquitylation	K752	-0.663		_CGEALGLK(gl)QAVK_
GTF2IRD2B	Phosphorylation	S830	1.307		_KINS(ph)SPNVNTTASGVEDLNIIQVTIPDDDNER_
IKBKG	Ubiquitylation	K285	-1.202	-0.389	_QEVIDKLK(gl)EEAEQHK_
IKBKG	Ubiquitylation	K309	0.123	0.725	_AQADIYK(gl)ADFQAER_
IKBKG	Ubiquitylation	K344		0.060	_LK(gl)ASCQESAR_
IKBKG	Phosphorylation	S387	-1.270	-1.418	_S(ph)PPEEPPDFCCPK_
NFKB1	Phosphorylation	S907	-0.025	0.113	_TTSQAHSLPLS(ph)PASTR_
NFKB2	Ubiquitylation	K741		-2.393	_GHTPLDLTCSTK(gl)VK_
NFKB2	Ubiquitylation	K743	-0.624		_GHTPLDLTCSTKVK(gl)_
RPL30	Ubiquitylation	K9	1.368		_K(gl)SLESINSR_
RPL30	Ubiquitylation	K23	2.101	1.951	_LQLVMK(gl)SGK_
RPL30	Ubiquitylation	K26	1.221	1.725	_SGK(gl)YVLGYK_
RPL30	Ubiquitylation	K32	2.603	2.249	_YVLGYK(gl)QTLK_
RPL30	Ubiquitylation	K44	2.004	3.213	_AK(gl)LVILANNCPALR_
RPL30	Ubiquitylation	K115	2.638	2.666	_SMPEQTGEK(gl)_
RPL6	Ubiquitylation	K87		1.333	_EK(gl)VLATVTKPVGGDK_
RPL6	Ubiquitylation	K94	1.709	2.117	_VLATVTK(gl)PVGGDK_
RPL6	Ubiquitylation	K100	1.045		_VLATVTKPVGGDK(gl)NGGTR_
RPL6	Ubiquitylation	K124	2.236		_K(gl)LLSHGK_
RPL6	Ubiquitylation	K131	1.708		_K(gl)PFSQHVR_
RPL6	Ubiquitylation	K193	1.849	1.791	_THQK(gl)FVIATSTK_
RPL6	Ubiquitylation	K208	1.353	1.717	_IDISNVK(gl)IPK_
RPL6	Ubiquitylation	K211	1.418		_IPK(gl)HLTDAYFK_
RPL6	Ubiquitylation	K219	1.861	2.486	_HLTDAYFK(gl)K_
RPL6	Ubiquitylation	K220	1.764	1.991	_HLTDAYFKK(gl)_
RPL6	Ubiquitylation	K252	1.097	1.710	_KIDQK(gl)AVDSQILPK_
RPL6	Ubiquitylation	K263	1.030	1.767	_IK(gl)AIPQLQGYLR_
RPS13	Ubiquitylation	K27	0.373		_SVPTWLK(gl)LTSDDVK_
RPS13	Ubiquitylation	K34	0.701		_LTSDDVK(gl)EQIYK_
RPS13	Ubiquitylation	K39	2.149	3.003	_EQIYK(gl)LAK_
RPS13	Ubiquitylation	K43	0.350	2.293	_K(gl)GLTPSQIGVILR_

Results for the Category TNF-alpha/Nf-kappa B signaling complex (RPL6, RPL30, RPS13, CHUK, DDX3X, NFKB2, NFKBIB, REL, IKBKG, NFKB1, MAP3K8, RELB, GLG1, NFKBIA, RELA, TNIP2, GTF2I) (5232)

Protein Results:

PTM Sites:

Results for the Category
TNF-alpha/Nf-kappa B signaling complex (RPL6, RPL30, RPS13, CHUK, DDX3X, NFKB2, NFKBIB, REL, IKBKG, NFKB1, MAP3K8, RELB, GLG1, NFKBIA, RELA, TNIP2, GTF2I)
(5232)