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Query: RPL6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RPL6 2 5.030 -0.910 1.320 0.056 -0.616 0.395 -0.617 -0.229

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RPL6 Ubiquitylation K219 1.861 2.486 _HLTDAYFK(gl)K_
RPL6 Ubiquitylation K94 1.709 2.117 _VLATVTK(gl)PVGGDK_
RPL6 Ubiquitylation K220 1.764 1.991 _HLTDAYFKK(gl)_
RPL6 Ubiquitylation K193 1.849 1.791 _THQK(gl)FVIATSTK_
RPL6 Ubiquitylation K263 1.030 1.767 _IK(gl)AIPQLQGYLR_
RPL6 Ubiquitylation K208 1.353 1.717 _IDISNVK(gl)IPK_
RPL6 Ubiquitylation K252 1.097 1.710 _KIDQK(gl)AVDSQILPK_
RPL6 Ubiquitylation K87 1.333 _EK(gl)VLATVTKPVGGDK_
RPL6 Ubiquitylation K100 1.045 _VLATVTKPVGGDK(gl)NGGTR_
RPL6 Ubiquitylation K124 2.236 _K(gl)LLSHGK_
RPL6 Ubiquitylation K131 1.708 _K(gl)PFSQHVR_
RPL6 Ubiquitylation K211 1.418 _IPK(gl)HLTDAYFK_

Background Information for RPL6:


Pubmed-RPL6 »
Uniprot-RPL6 »
Biogrid-RPL6 »
ProteomicsDB-RPL6 »

Tumorportal-RPL6 »
COSMIC-RPL6 »
GenomeRNAi-RPL6 »
Genecards-RPL6


Protein-protein Interactions for RPL6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C17orf85 Cat. description Hein, Mann, Cell 2015
Category members IP bait CD2AP Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3E Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait IBTK Cat. description Hein, Mann, Cell 2015
Category members IP bait MAX Cat. description Hein, Mann, Cell 2015
Category members IP bait MBD2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait NPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP98 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC5 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPX2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRIP11 Cat. description Hein, Mann, Cell 2015
Category members IP bait CNBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAGEB10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL28 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL37A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SART3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RPL6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Translation_prot_SH3-like IPR008991 0.29


Protein complexes (CORUM database) featuring RPL6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3055 Nop56p-associated pre-rRNA complex Database INF
Category members Corum 306 Ribosome, cytoplasmic Database INF
Category members Corum 308 60S ribosomal subunit, cytoplasmic Database INF
Category members Corum 5266 TNF-alpha/NF-kappa B signaling complex 6 Database 3.74
Category members Corum 5232 TNF-alpha/Nf-kappa B signaling complex (RPL6, RPL30, RPS13, CHUK, DDX3X, NFKB2, NFKBIB, REL, IKBKG, NFKB1, MAP3K8, RELB, GLG1, NFKBIA, RELA, TNIP2, GTF2I) Database 0.09


Categories featuring RPL6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members Pathway Pathway_369 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION 0 INF
Category members Pathway Pathway_371 REACTOME_INFLUENZA_LIFE_CYCLE 0 INF
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members Pathway Pathway_459 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 0 INF
Category members Pathway Pathway_768 REACTOME_PEPTIDE_CHAIN_ELONGATION 0 INF
Category members Pathway Pathway_770 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 0 INF
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_772 KEGG_RIBOSOME 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members Pathway Pathway_774 REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION 0 INF
Category members GO Category GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Database INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0003735 structural constituent of ribosome Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006413 translational initiation Database INF
Category members GO Category GO:0006414 translational elongation Database INF
Category members GO Category GO:0006415 translational termination Database INF
Category members GO Category GO:0006614 SRP-dependent cotranslational protein targeting to membrane Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members GO Category GO:0019058 viral life cycle Database INF
Category members GO Category GO:0019083 viral transcription Database INF
Category members GO Category GO:0022625 cytosolic large ribosomal subunit Database INF
Category members GO Category GO:0005840 ribosome Database 12.2
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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