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MGC1-DNA-PKcs-Ku complex
(5176)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
MDC1 3 0.550 -0.700
PRKDC 3 1.430 -1.280 -0.994 -0.672 -0.244 0.307 0.443
XRCC5 0 1.940 -0.800 0.205 -0.587 0.234 -0.176 0.162
XRCC6 0 0.960 -0.800
XRCC6 0 0.960 -0.800 -0.089 -0.758 0.145 0.033 0.140

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
MDC1 Phosphorylation S168 0.788 0.909 _LLLAEDS(ph)EEEVDFLSER_
MDC1 Phosphorylation S329 -0.069 -0.749 _AQPFGFIDS(ph)DTDAEEERIPATPVVIPMK_
MDC1 Phosphorylation T331 -0.735 -0.646 _AQPFGFIDSDT(ph)DAEEERIPATPVVIPMKK_
MDC1 Phosphorylation S376 -0.196 -0.279 _GPGAPGLAHLQESQAGS(ph)DTDVEEGKAPQAVPLEK_
MDC1 Phosphorylation T378 -0.401 _GPGAPGLAHLQESQAGSDT(ph)DVEEGK_
MDC1 Phosphorylation T404 -0.050 _SQASMVINSDT(ph)DDEEEVSAALTLAHLK_
MDC1 Phosphorylation S453 0.346 _SQTTTERDS(ph)DTDVEEEELPVENR_
MDC1 Phosphorylation T455 -0.574 _SQTTTERDSDT(ph)DVEEEELPVENR_
MDC1 Ubiquitylation K472 -0.332 _EAVLK(gl)DHTK_
MDC1 Ubiquitylation K476 -0.040 _EAVLKDHTK(gl)IR_
MDC1 Phosphorylation S485 0.170 -0.259 _AHS(ph)EKDQPPFGDSDDSVEADK_
MDC1 Phosphorylation S513 3.827 3.443 _S(ph)QASTTVDINTQVEK_
MDC1 Phosphorylation Y775 -0.566 _ESEDSETQPFDTHLEAY(ph)GPCLSPPR_
MDC1 Phosphorylation S780 -0.852 -0.642 _ESEDSETQPFDTHLEAYGPCLS(ph)PPR_
MDC1 Phosphorylation S793 -0.391 -0.332 _AIPGDQHPES(ph)PVHTEPM(ox)GIQGR_
MDC1 Phosphorylation S986 -1.929 _GQASSPTPEPGVGAGDLPGPTSAPVPS(ph)GSQSGGRGSPVSPR_
MDC1 Phosphorylation S995 -0.793 _GQAS(ph)SPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGS(ph)PVSPR_
MDC1 Phosphorylation S1086 1.806 _TRQDGS(ph)QEAPEAPLSSELEPFHPKPK_
MDC1 Phosphorylation T1157 -0.188 _SSVKT(ph)PEPVVPTAPELQPSTSTDQPVTSEPTSQVTR_
MDC1 Phosphorylation S1194 0.770 _S(ph)SVKTPETVVPTALELQPSTSTDRPVTSEPTSQATR_
MDC1 Phosphorylation T1198 0.898 _SSVKT(ph)PETVVPTALELQPSTSTDRPVTSEPTSQATR_
MDC1 Phosphorylation T1239 -1.231 _SSVKT(ph)PEPVVPTAPELQPSTSTDQPVTSEPTYQATR_
MDC1 Phosphorylation T1384 -1.318 _NPESTVPIAPELPPSTSTEQPVT(ph)PEPTSR_
MDC1 Phosphorylation S1399 -0.366 _NRS(ph)SGKTPETLVPTAPK_
MDC1 Phosphorylation S1417 -0.579 _LEPS(ph)TSTDQPVT(ph)PEPTSQATR_
MDC1 Phosphorylation S1419 -0.152 0.059 _LEPSTS(ph)TDQPVTPEPTSQATR_
MDC1 Phosphorylation T1425 0.018 -0.167 _LEPSTSTDQPVT(ph)PEPTSQATR_
MDC1 Phosphorylation T1444 -0.989 _SSVKT(ph)PETVVPTAPELQPSTSTDQPVTPEPTSQATR_
MDC1 Phosphorylation T1466 5.092 _SSVKT(ph)PETVVPTAPELQPSTSTDQPVT(ph)PEPTSQATR_
MDC1 Phosphorylation T1488 -0.511 _SSVKTPET(ph)VVPTAPELQASASTDQPVTSEPTSR_
MDC1 Phosphorylation T1541 -1.076 _TPETVVPAAPELQPST(ph)STDQPVTPEPTSR_
MDC1 Phosphorylation T1548 -1.262 -1.584 _TPETVVPAAPELQPSTSTDQPVT(ph)PEPTSR_
MDC1 Phosphorylation T1567 0.014 0.330 _SSVKT(ph)PESIVPIAPELQPSTSR_
MDC1 Phosphorylation T1589 -0.952 -0.451 _NQLVT(ph)PEPTSR_
MDC1 Phosphorylation T1608 -0.490 -1.272 _SSVKT(ph)PEPVVPTAPEPHPTTSTDQPVTPK_
MDC1 Phosphorylation T1630 -1.705 _SSVKT(ph)PEPVVPTAPEPHPTTSTDQPVT(ph)PK_
MDC1 Phosphorylation T1671 0.063 _TPKPVEPAASDLEPFTPTDQSVT(ph)PEAIAQGGQSK_
MDC1 Phosphorylation S1775 0.591 -0.039 _AAESLTAIPEPAS(ph)PQLLETPIHASQIQK_
MDC1 Phosphorylation S1797 -0.582 -0.634 _S(ph)RFTPELQPK_
MDC1 Phosphorylation T1800 -0.475 -0.235 _SRFT(ph)PELQPK_
MDC1 Phosphorylation S1820 0.073 0.144 _SLATMDS(ph)PPHQK_
MDC1 Ubiquitylation K1885 1.530 _TK(gl)LNQESTAPK_
PRKDC Ubiquitylation K108 0.568 -0.049 _IAPYSVEIK(gl)NTCTSVYTK_
PRKDC Ubiquitylation K117 0.540 0.376 _NTCTSVYTK(gl)DR_
PRKDC Ubiquitylation K163 0.679 _FYGELALK(gl)K_
PRKDC Ubiquitylation K164 -0.371 _FYGELALKK(gl)_
PRKDC Ubiquitylation K263 0.272 -0.659 _AIRPQIDLK(gl)R_
PRKDC Ubiquitylation K357 1.479 _NVDSNNK(gl)ELSIAIR_
PRKDC Ubiquitylation K374 -0.342 _GYGLFAGPCK(gl)VINAK_
PRKDC Ubiquitylation K493 -0.582 _ICSK(gl)PVVLPK_
PRKDC Ubiquitylation K689 -0.187 _YFEGVSPK(gl)SLK_
PRKDC Ubiquitylation K810 0.561 0.360 _TSALSDETK(gl)NNWEVSALSR_
PRKDC Ubiquitylation K828 0.723 -0.203 _GFNK(gl)VVLK_
PRKDC Ubiquitylation K832 1.611 -0.278 _VVLK(gl)HLK_
PRKDC Ubiquitylation K838 1.939 1.087 _TK(gl)NLSSNEAISLEEIR_
PRKDC Ubiquitylation K963 -1.201 _ATQMPEGGQGAPPMYQLYK(gl)R_
PRKDC Ubiquitylation K1038 0.646 _EFLK(gl)WSIK_
PRKDC Ubiquitylation K1042 -0.070 -0.432 _WSIK(gl)QITPQQQEK_
PRKDC Ubiquitylation K1051 -1.153 _QITPQQQEK(gl)SPVNTK_
PRKDC Ubiquitylation K1057 -0.693 _SPVNTK(gl)SLFK_
PRKDC Ubiquitylation K1334 0.108 _YNYSK(gl)CTVVVR_
PRKDC Ubiquitylation K1407 -0.971 _ALK(gl)MSPYK_
PRKDC Ubiquitylation K1456 0.657 -0.495 _LAAVVSACK(gl)QLHR_
PRKDC Ubiquitylation K1744 -0.269 _FNNYVDCMK(gl)K_
PRKDC Ubiquitylation K1857 -0.152 _FTK(gl)LNESTFDTQITK_
PRKDC Ubiquitylation K1869 0.803 _LNESTFDTQITK(gl)K_
PRKDC Ubiquitylation K1870 0.843 -0.566 _LNESTFDTQITKK(gl)_
PRKDC Ubiquitylation K1892 -1.132 -1.666 _LPKDDVHAK(gl)ESK_
PRKDC Ubiquitylation K2418 -0.499 _SK(gl)DFVQVMR_
PRKDC Ubiquitylation K2447 -0.500 -1.069 _LK(gl)PVELR_
PRKDC Phosphorylation S2612 -0.226 1.740 _STVLTPMFVETQAS(ph)QGTLQTR_
PRKDC Phosphorylation T2671 -0.097 _SSFDWLTGSSTDPLVDHT(ph)SPSSDSLLFAHK_
PRKDC Phosphorylation S2672 0.083 _SSFDWLTGSSTDPLVDHTS(ph)PSSDSLLFAHK_
PRKDC Phosphorylation S2675 -0.193 _SSFDWLTGSSTDPLVDHTSPSS(ph)DSLLFAHK_
PRKDC Phosphorylation S2677 0.284 -0.009 _SSFDWLTGSSTDPLVDHTSPSSDS(ph)LLFAHK_
PRKDC Ubiquitylation K2694 -1.865 _APLK(gl)SVGPDFGKK_
PRKDC Ubiquitylation K2703 0.600 _SVGPDFGKK(gl)_
PRKDC Ubiquitylation K2715 0.258 -1.356 _LGLPGDEVDNK(gl)VK_
PRKDC Ubiquitylation K2717 -1.795 _LGLPGDEVDNKVK(gl)GAAGR_
PRKDC Ubiquitylation K2738 -0.251 -0.421 _DQEK(gl)LSLMYAR_
PRKDC Ubiquitylation K2758 -0.370 _EKEIK(gl)SELK_
PRKDC Ubiquitylation K2764 0.293 -0.445 _MK(gl)QDAQVVLYR_
PRKDC Ubiquitylation K2829 -1.122 _TLSEK(gl)NNITQK_
PRKDC Ubiquitylation K2908 -0.765 -1.790 _LLPAELPAK(gl)R_
PRKDC Ubiquitylation K2928 0.416 -0.319 _WVELAK(gl)LYR_
PRKDC Ubiquitylation K3158 0.005 -1.352 _QGNLSSQVPLK(gl)R_
PRKDC Ubiquitylation K3192 -0.192 _CFFLSK(gl)IEEK_
PRKDC Phosphorylation S3205 2.096 1.572 _LTPLPEDNS(ph)M(ox)NVDQDGDPSDR_
PRKDC Ubiquitylation K3235 0.810 0.153 _SCK(gl)FSMK_
PRKDC Ubiquitylation K3241 0.107 -0.523 _MK(gl)MIDSAR_
PRKDC Ubiquitylation K3248 0.977 -0.289 _K(gl)QNNFSLAMK_
PRKDC Ubiquitylation K3260 0.018 -1.258 _LLK(gl)ELHK_
PRKDC Ubiquitylation K3455 0.488 -0.615 _ALK(gl)LNSNEAR_
PRKDC Ubiquitylation K3552 1.164 0.277 _NK(gl)EFVAR_
PRKDC Ubiquitylation K3608 1.045 1.399 _NIEK(gl)MYER_
PRKDC Ubiquitylation K3631 -1.002 _K(gl)FIQTFGK_
PRKDC Ubiquitylation K3650 0.475 -0.515 _GGSK(gl)LLR_
PRKDC Ubiquitylation K3710 0.119 -0.965 _GK(gl)PLPEYHVR_
PRKDC Ubiquitylation K3877 0.018 -2.000 _ESK(gl)VPADLLKR_
PRKDC Ubiquitylation K3884 -0.255 -1.203 _VPADLLK(gl)R_
PRKDC Ubiquitylation K4019 -0.937 _NFEQK(gl)MLK_
PRKDC Ubiquitylation K4023 -0.481 _K(gl)GGSWIQEINVAEK_
XRCC5 Ubiquitylation K195 -0.495 -0.075 _LGGHGPSFPLK(gl)GITEQQK_
XRCC5 Ubiquitylation K265 -0.577 0.489 _IAAYK(gl)SILQER_
XRCC5 Ubiquitylation K282 0.763 _TWTVVDAK(gl)TLKK_
XRCC5 Ubiquitylation K325 0.022 -0.122 _YGSDIVPFSK(gl)VDEEQMK_
XRCC5 Ubiquitylation K332 -0.032 0.491 _VDEEQMK(gl)YK_
XRCC5 Ubiquitylation K347 0.588 1.044 _CFSVLGFCK(gl)SSQVQR_
XRCC5 Ubiquitylation K481 -1.648 0.087 _TDTLEDLFPTTK(gl)IPNPR_
XRCC5 Ubiquitylation K532 0.343 -0.001 _SQIPLSK(gl)IK_
XRCC5 Ubiquitylation K534 -0.146 0.207 _SQIPLSKIK(gl)_
XRCC5 Ubiquitylation K543 0.666 0.157 _TLFPLIEAK(gl)KK_
XRCC5 Ubiquitylation K544 0.165 0.157 _TLFPLIEAKK(gl)_
XRCC5 Ubiquitylation K660 0.644 1.285 _FNNFLK(gl)ALQEK_
XRCC5 Ubiquitylation K665 0.630 0.990 _ALQEK(gl)VEIK_
XRCC5 Ubiquitylation K702 0.626 0.332 _EEASGSSVTAEEAK(gl)K_
XRCC5 Ubiquitylation K703 0.743 0.332 _EEASGSSVTAEEAKK(gl)_
XRCC6 Phosphorylation S27 0.932 0.873 _TEGDEEAEEEQEENLEAS(ph)GDYK_
XRCC6 Ubiquitylation K114 -0.534 -0.728 _NIYVLQELDNPGAK(gl)R_
XRCC6 Ubiquitylation K123 -0.756 _ILELDQFK(gl)GQQGQK_
XRCC6 Ubiquitylation K129 0.079 -0.683 _ILELDQFKGQQGQK(gl)R_
XRCC6 Ubiquitylation K182 -1.603 _IMLFTNEDNPHGNDSAK(gl)ASR_
XRCC6 Ubiquitylation K282 -2.587 _ALK(gl)PPPIK_
XRCC6 Ubiquitylation K287 -1.436 -2.286 _ALKPPPIK(gl)LYR_
XRCC6 Ubiquitylation K299 -0.535 -0.792 _ETNEPVKTK(gl)TR_
XRCC6 Ubiquitylation K317 -0.584 -0.964 _TFNTSTGGLLLPSDTK(gl)R_
XRCC6 Ubiquitylation K331 -1.666 _QIILEK(gl)EETEELKR_
XRCC6 Ubiquitylation K338 -1.479 -1.003 _QIILEKEETEELK(gl)R_
XRCC6 Ubiquitylation K451 -1.713 -1.901 _MPFTEK(gl)IMATPEQVGK_
XRCC6 Phosphorylation T455 -0.085 0.348 _IMAT(ph)PEQVGK_
XRCC6 Ubiquitylation K461 0.239 -0.409 _IMATPEQVGK(gl)MK_
XRCC6 Ubiquitylation K463 -0.609 -0.641 _MK(gl)AIVEK_
XRCC6 Ubiquitylation K468 -1.302 -0.451 _AIVEK(gl)LR_
XRCC6 Phosphorylation S475 1.136 0.167 _S(ph)DSFENPVLQQHFR_
XRCC6 Phosphorylation S477 1.023 0.034 _SDS(ph)FENPVLQQHFR_
XRCC6 Ubiquitylation K516 -1.089 _VEAMNK(gl)R_
XRCC6 Phosphorylation S560 0.318 0.378 _VEYS(ph)EEELKTHISK_
XRCC6 Ubiquitylation K565 0.021 -0.887 _VEYSEEELK(gl)THISK_
XRCC6 Ubiquitylation K575 0.031 -0.121 _GTLGK(gl)FTVPMLK_
XRCC6 Ubiquitylation K591 0.474 0.187 _AYGLK(gl)SGLK_


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