Results for the Category
MSH2-MLH1-PMS2-PCNA DNA-repair initiation complex
(290)
RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
W | |||||||
Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
---|---|---|---|---|---|---|---|---|
PCNA | 2 | -0.730 | 0.380 | 0.679 | 1.154 | 0.572 | 0.718 | 0.782 |
MSH2 | 1 | -0.130 | 0.010 | 0.224 | 0.457 | 0.838 | 0.840 | 0.366 |
MLH1 | 0 | -0.460 | 0.110 | -0.360 | 1.227 | 1.219 | ||
PMS2 | 0 | 0.410 | -0.450 |
Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
---|---|---|---|---|---|
MSH2 | Ubiquitylation | K212 | -0.233 | _ECVLPGGETAGDMGK(gl)LR_ | |
MSH2 | Ubiquitylation | K249 | 0.461 | _K(gl)GEQMNSAVLPEMENQVAVSSLSAVIK_ | |
MSH2 | Ubiquitylation | K347 | 2.867 | _LVNQWIK(gl)QPLMDK_ | |
MSH2 | Ubiquitylation | K531 | 1.040 | _VTCKEEK(gl)VLR_ | |
MSH2 | Ubiquitylation | K555 | 0.164 | _FTNSK(gl)LTSLNEEYTK_ | |
MSH2 | Ubiquitylation | K635 | -0.376 | _IILK(gl)ASR_ | |
PCNA | Ubiquitylation | K13 | 0.209 | 2.207 | _LVQGSILK(gl)K_ |
PCNA | Ubiquitylation | K14 | 0.233 | 2.833 | _LVQGSILKK(gl)_ |
PCNA | Ubiquitylation | K80 | 0.570 | 1.579 | _ILK(gl)CAGNEDIITLR_ |
PCNA | Ubiquitylation | K164 | 2.309 | 2.671 | _DLSHIGDAVVISCAK(gl)DGVK_ |
PCNA | Ubiquitylation | K168 | 2.484 | 2.645 | _DLSHIGDAVVISCAKDGVK(gl)_ |
PCNA | Ubiquitylation | K248 | 0.226 | 0.515 | _IADMGHLK(gl)YYLAPK_ |
PMS2 | Ubiquitylation | K146 | -0.403 | _IIQK(gl)TPYPRPR_ |
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