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Query: ZRSR2

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ZRSR2 0 -0.076 0.620 -0.290

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ZRSR2 Phosphorylation S349 -0.162 0.086 _DIYLS(ph)PDR_
ZRSR2 Phosphorylation S384 0.014 _RNPS(ph)PDHSYK_

Background Information for ZRSR2:


Pubmed-ZRSR2 »
Uniprot-ZRSR2 »
Biogrid-ZRSR2 »
ProteomicsDB-ZRSR2 »

Tumorportal-ZRSR2 »
COSMIC-ZRSR2 »
GenomeRNAi-ZRSR2 »
Genecards-ZRSR2


Protein-protein Interactions for ZRSR2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EMC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC97 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZCRB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZRSR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ZRSR2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members RRM_dom_euk IPR003954 0.18
Category members Znf_CCCH IPR000571 0.03
Category members U2_small IPR009145 0


Protein complexes (CORUM database) featuring ZRSR2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 430 18S U11/U12 snRNP Database 0.29


Categories featuring ZRSR2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0000245 spliceosomal complex assembly Database 0.39
Category members GO Category GO:0005689 U12-type spliceosomal complex Database 0.29
Category members GO Category GO:0030628 pre-mRNA 3'-splice site binding Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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