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Query: ZNF281

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ZNF281 0 -1.080 1.890 -0.960
ZNF281 0 -1.080 1.890 -0.960 -1.258 0.818 1.187 -0.499

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ZNF281 Phosphorylation S651 0.362 0.137 _VDLHTSGEHSELVQEENLS(ph)PGTQTPSNDK_
ZNF281 Phosphorylation T888 0.078 -0.076 _VKT(ph)PTSQSYR_
ZNF281 Ubiquitylation K622 -1.827 _SESQK(gl)EDPFNIAEPR_
ZNF281 Phosphorylation T654 0.273 _VDLHTSGEHSELVQEENLSPGT(ph)QTPSNDK_

Background Information for ZNF281:





Protein-protein Interactions for ZNF281

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCT7 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM190B Cat. description Hein, Mann, Cell 2015
Category members IP bait LGALS3BP Cat. description Hein, Mann, Cell 2015
Category members IP bait NIPSNAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED10 Cat. description Hein, Mann, Cell 2015
Category members IP bait TNPO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TP53BP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZNF281 Cat. description Hein, Mann, Cell 2015
Category members IP bait C6orf141 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDC16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait L3MBTL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPXN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ZNF281

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_C2H2-like IPR015880 1.29
Category members Znf_C2H2 IPR007087 0.92


Protein complexes (CORUM database) featuring ZNF281

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3075 UTX-MLL2/3 complex Database 0


Categories featuring ZNF281

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0001047 core promoter binding Database 0.11
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0010172 embryonic body morphogenesis Database 0
Category members GO Category GO:0010629 negative regulation of gene expression Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0048863 stem cell differentiation Database 0


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