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Query: WNK3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WNK3 0 1.162 -0.110 -0.490 0.546 0.639

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WNK3 Phosphorylation S2530 0.202 -0.225 _DVDDGSGSPHS(ph)PHQLSSK_
WNK3 Phosphorylation S2509 -0.298 _KEKPELSEPSHLNGPS(ph)SDPEAAFLSR_
WNK3 Phosphorylation S2510 -0.532 -0.298 _KEKPELSEPSHLNGPSS(ph)DPEAAFLSR_
WNK3 Phosphorylation S2503 -0.810 -0.764 _KEKPELSEPS(ph)HLNGPSSDPEAAFLSR_
WNK3 Phosphorylation S2476 -0.727 -0.899 _KEGPVAS(ph)PPFMDLEQAVLPAVIPK_
WNK3 Phosphorylation S2527 -0.349 _DVDDGSGS(ph)PHSPHQLSSK_

Background Information for WNK3:


Pubmed-WNK3 »
Uniprot-WNK3 »
Biogrid-WNK3 »
ProteomicsDB-WNK3 »

Tumorportal-WNK3 »
COSMIC-WNK3 »
GenomeRNAi-WNK3 »
Genecards-WNK3


Protein-protein Interactions for WNK3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KLHL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSC22D4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in WNK3
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring WNK3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring WNK3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005923 tight junction Database 0.69
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0005912 adherens junction Database 0.25
Category members GO Category GO:0046777 protein autophosphorylation Database 0.23
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0010765 positive regulation of sodium ion transport Database 0
Category members GO Category GO:0010800 positive regulation of peptidyl-threonine phosphorylation Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0032414 positive regulation of ion transmembrane transporter activity Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0051928 positive regulation of calcium ion transport Database 0


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