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Query: WLS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WLS 0 1.067 -0.540 1.290

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WLS Ubiquitylation K410 0.878 _NISGK(gl)QSSLPAMSK_
WLS Ubiquitylation K13 0.869 _AGAIIENMSTKK(gl)_
WLS Ubiquitylation K217 -1.452 0.710 _INVGIGEIK(gl)DIR_
WLS Ubiquitylation K419 -1.101 0.564 _QSSLPAMSK(gl)VR_
WLS Ubiquitylation K168 0.058 _CTFTSPK(gl)TPEHEGR_
WLS Ubiquitylation K206 -0.013 _LPVNEK(gl)K_
WLS Ubiquitylation K207 -2.023 _LPVNEKK(gl)_

Background Information for WLS:


Pubmed-WLS »
Uniprot-WLS »
Biogrid-WLS »
ProteomicsDB-WLS »

Tumorportal-WLS »
COSMIC-WLS »
GenomeRNAi-WLS »
Genecards-WLS


Protein-protein Interactions for WLS
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHRND Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GABRA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR3C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMED6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in WLS
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring WLS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring WLS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members GO Category GO:0031901 early endosome membrane Database 0.58
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0001707 mesoderm formation Database 0.11
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members GO Category GO:0017147 Wnt-protein binding Database 0.02
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0009948 anterior/posterior axis specification Database 0
Category members GO Category GO:0031410 cytoplasmic vesicle Database 0
Category members GO Category GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling Database 0


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