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Query: VRK2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
VRK2 0 -0.922 0.750 -0.170 -0.922

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for VRK2:


Pubmed-VRK2 »
Uniprot-VRK2 »
Biogrid-VRK2 »
ProteomicsDB-VRK2 »

Tumorportal-VRK2 »
COSMIC-VRK2 »
GenomeRNAi-VRK2 »
Genecards-VRK2


Protein-protein Interactions for VRK2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LDHD Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM187B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPINT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SRPRB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMPRSS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNRF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in VRK2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0


Protein complexes (CORUM database) featuring VRK2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring VRK2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0046777 protein autophosphorylation Database 0.23
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0031966 mitochondrial membrane Database 0
Category members GO Category GO:0034599 cellular response to oxidative stress Database 0
Category members GO Category GO:0043408 regulation of MAPK cascade Database 0


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