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Query: VPS45

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
VPS45 2 8.391 -1.960 4.060
VPS45 2 8.391 -1.960 4.060 0.939 1.074

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
VPS45 Ubiquitylation K330 1.737 _M(ox)SGTVSK(gl)HVTVVGELSR_
VPS45 Ubiquitylation K450 0.498 0.947 _DAVAITK(gl)QFLK_
VPS45 Ubiquitylation K297 -0.027 0.174 _NLMEDFQKK(gl)_
VPS45 Ubiquitylation K192 0.231 0.142 _LAECVK(gl)QVITK_
VPS45 Ubiquitylation K454 -0.293 -0.013 _QFLK(gl)GLK_
VPS45 Ubiquitylation K257 -0.698 -0.241 _VPGISK(gl)DLR_
VPS45 Ubiquitylation K185 -0.309 _YQLSSEAAK(gl)R_
VPS45 Ubiquitylation K483 -2.673 -0.766 _LK(gl)ENLYPYLGPSTLR_
VPS45 Ubiquitylation K443 -0.539 -0.864 _GSDLFSPK(gl)DAVAITK_
VPS45 Ubiquitylation K304 0.581 _EQQK(gl)LESIADMK_
VPS45 Ubiquitylation K378 0.005 _LLQNPK(gl)VTEFDAAR_

Background Information for VPS45:


Pubmed-VPS45 »
Uniprot-VPS45 »
Biogrid-VPS45 »
ProteomicsDB-VPS45 »

Tumorportal-VPS45 »
COSMIC-VPS45 »
GenomeRNAi-VPS45 »
Genecards-VPS45


Protein-protein Interactions for VPS45
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait LSR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NIPAL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAMP4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VPS45 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VTI1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZFYVE20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in VPS45
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Sec1-like IPR001619 1.02


Protein complexes (CORUM database) featuring VPS45
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring VPS45
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0006904 vesicle docking involved in exocytosis Database 0.51
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0010008 endosome membrane Database 0


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