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Query: VPS18

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
VPS18 0 -2.286 -0.130 -0.260 -0.775 -0.482

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
VPS18 Ubiquitylation K46 -1.029 _EVPIFTK(gl)QR_

Background Information for VPS18:





Protein-protein Interactions for VPS18

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait VPS11 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS16 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS18 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS41 Cat. description Hein, Mann, Cell 2015
Category members IP bait C18orf1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CXorf48 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TECPR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UXS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VIPR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VPS11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VPS41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in VPS18

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Clathrin_H-chain/VPS_repeat IPR000547 0


Protein complexes (CORUM database) featuring VPS18

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 944 Class C Vps complex (VPS11, VPS18, VPS16) Database 0.34
Category members Corum 2573 Class C VPS/HOPS complex Database 0
Category members Corum 943 Class C Vps complex (VPS11, VPS18, STX7) Database 0


Categories featuring VPS18

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0005769 early endosome Database 1.26
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0030897 HOPS complex Database 0.13
Category members GO Category GO:0007032 endosome organization Database 0.11
Category members GO Category GO:0005884 actin filament Database 0.08
Category members GO Category GO:0007040 lysosome organization Database 0
Category members GO Category GO:0031902 late endosome membrane Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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