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Query: USP46

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
USP46 0 1.261 0.220 0.340

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
USP46 Ubiquitylation K273 0.375 0.547 _YTK(gl)LSYR_

Background Information for USP46:





Protein-protein Interactions for USP46

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHRM3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GORASP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IFI30 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IGFBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAD51AP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF19B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THUMPD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPYL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in USP46

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UCH/PAN2 IPR028889 0.62
Category members Peptidase_C19_UCH IPR001394 0.53


Protein complexes (CORUM database) featuring USP46

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring USP46

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0004843 ubiquitin-specific protease activity Database 3.28
Category members GO Category GO:0004221 ubiquitin thiolesterase activity Database 1.36
Category members GO Category GO:0016579 protein deubiquitination Database 1.32
Category members GO Category GO:0032228 regulation of synaptic transmission, GABAergic Database 0.19
Category members GO Category GO:0007610 behavior Database 0.04
Category members GO Category GO:0001662 behavioral fear response Database 0


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