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Query: USP39

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
USP39 1 4.753 -0.890 1.910 0.215 0.205 0.107 -0.550 -0.100

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
USP39 Phosphorylation S43 -0.046 1.159 _EPEAASS(ph)RGSPVR_
USP39 Phosphorylation S82 0.415 0.295 _EVDEDS(ph)EPEREVR_
USP39 Phosphorylation S46 1.807 0.030 _EPEAASSRGS(ph)PVR_

Background Information for USP39:


Pubmed-USP39 »
Uniprot-USP39 »
Biogrid-USP39 »
ProteomicsDB-USP39 »

Tumorportal-USP39 »
COSMIC-USP39 »
GenomeRNAi-USP39 »
Genecards-USP39


Protein-protein Interactions for USP39
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHMP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRPF4 Cat. description Hein, Mann, Cell 2015
Category members IP bait SART1 Cat. description Hein, Mann, Cell 2015


Protein Domains in USP39
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UCH/PAN2 IPR028889 0.62
Category members Peptidase_C19_UCH IPR001394 0.53
Category members Znf_UBP IPR001607 0.05


Protein complexes (CORUM database) featuring USP39
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3


Categories featuring USP39
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0004221 ubiquitin thiolesterase activity Database 1.36
Category members GO Category GO:0051301 cell division Database 1.15
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0000245 spliceosomal complex assembly Database 0.39
Category members GO Category GO:0008270 zinc ion binding Database 0.29


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