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Query: UBR1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UBR1 0 -1.405 -0.510 0.110

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UBR1 Ubiquitylation K596 0.045 _TVVQSCGHSLETK(gl)SYR_
UBR1 Phosphorylation T21 -0.158 _MEISAELPQT(ph)PQR_
UBR1 Ubiquitylation K1681 -1.186 _VVLVEGK(gl)AR_
UBR1 Ubiquitylation K859 -2.925 _KQENK(gl)DEALPPPPPPEFCPAFSK_
UBR1 Ubiquitylation K1703 -1.402 _GCAYPAPYLDEYGETDPGLK(gl)R_

Background Information for UBR1:


Pubmed-UBR1 »
Uniprot-UBR1 »
Biogrid-UBR1 »
ProteomicsDB-UBR1 »

Tumorportal-UBR1 »
COSMIC-UBR1 »
GenomeRNAi-UBR1 »
Genecards-UBR1


Protein-protein Interactions for UBR1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MGP Cat. description Hein, Mann, Cell 2015
Category members IP bait NES Cat. description Hein, Mann, Cell 2015
Category members IP bait ADAMTS12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BMP7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C11orf66 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C18orf1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC130 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLCC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRHBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CROCC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB49 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GFAP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait INSL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ITM2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIPT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NXPH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDGFD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNLIPRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLDIP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRSS23 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RABGEF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCML4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPATA24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPINK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TGFB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VIM Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UBR1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_N-recognin IPR003126 0
Category members ClpS_core IPR003769 0
Category members Znf_N-recognin_met IPR013993 0
Category members Ribosomal_L7/12_C/ClpS-like IPR014719 0


Protein complexes (CORUM database) featuring UBR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring UBR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0000502 proteasome complex Database 3.17
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0030163 protein catabolic process Database 0.38
Category members GO Category GO:0070728 leucine binding Database 0.36
Category members GO Category GO:0032007 negative regulation of TOR signaling Database 0.33
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0000151 ubiquitin ligase complex Database 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0071233 cellular response to leucine Database 0


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